Abstract
A series of preparations of (3-N-[11C]methyl)spiperone in several basis conditions by means of an automated system incorporating an "on-line" methylation is reported. The radiochemical yield was observed to be strongly affected by the water content. For all the preparations the reaction temperature was 80°C and the reaction time 5 min. The influence of these two parameters on the radiochemical yield for the synthesis utilizing methanolic tetrabutylammonium hydroxide has been briefly examined.
| Original language | English |
|---|---|
| Pages (from-to) | 1526-1528 |
| Number of pages | 3 |
| Journal | International Journal of Radiation Applications and Instrumentation. Part |
| Volume | 43 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 1992 |
ASJC Scopus subject areas
- Radiation
Fingerprint Dive into the research topics of 'Comparative study on the influence of bases on (3-N-[<sup>11</sup>C]methyl)spiperone synthesis'. Together they form a unique fingerprint.
Cite this
Pascali, C., Iwata, R., & Ido, T. (1992). Comparative study on the influence of bases on (3-N-[11C]methyl)spiperone synthesis. International Journal of Radiation Applications and Instrumentation. Part, 43(12), 1526-1528. https://doi.org/10.1016/0883-2889(92)90185-H