Comparison among the available stone treatment techniques from the first European Association of Urology Section of Urolithiasis (EULIS) Survey: Do we have a queen?

Stefano Paolo Zanetti, Michele Talso, Franco Palmisano, Fabrizio Longo, Andrea Gallioli, Matteo Fontana, Elisa De Lorenzis, Gianluca Sampogna, Luca Boeri, Giancarlo Albo, Alberto Trinchieri, Emanuele Montanari

Research output: Contribution to journalArticlepeer-review


Purpose The miniaturization of instruments has had an impact on stone management. The aims of this study were to highlight surgeon preferences among Retrograde Intra Renal Surgery (RIRS), Regular, Mini-, UltraMini- and Micro- Percutaneous Nephrolithotomy (PCNL) for urolithiasis and to compare the effectiveness and safety of these techniques in a real-life setting. Methods A 12-item survey regarding endourological techniques was conducted through Survey Monkey among attendees of the 2013 European Association of Urology Section of Urolithiasis meeting. We asked responders to share data from the last 5 cases they performed for each technique. Procedures were stratified according to stone size and the centres’ surgical volume. Techniques were compared in terms of effectiveness and safety. Analyses were performed on the overall group and a subgroup of 1–2 cm stones. Results We collected data from a total of 420 procedures by 30, out of 78, urologists who received the survey (response rate 38%): 140 RIRS, 141 Regular-PCNL (>20 Ch), 67 Mini-PCNL (14–20 Ch), 28 UltraMini-PCNL (11–13 Ch) and 44 Micro-PCNL (4,8–8 Ch). Techniques choice was influenced by stone size and the centre’s surgical volume. Effectiveness and safety outcomes were influenced by stone size, independently of the technique. The stone-free rate was significantly lower in Micro-PCNL compared to Regular-PCNL. This was not confirmed for 1–2 cm stones. All techniques presented a lower complication rate than Regular-PCNL, with Mini-PCNL being the most protective technique compared to Regular-PCNL. Conclusions Stone size seems to drive treatment choice. Miniaturized PCNL techniques are widely employed for 1–2 cm stones, in particular in higher surgical volume centres. Mini-PCNL and RIRS are growing in popularity for stones > 2 cm. Mini-PCNL seems to be a good compromise, being the most effective and safe procedure among PCNL techniques. RIRS is characterized by satisfactory stone-free and low complication rates.

Original languageEnglish
Article numbere0205159
JournalPLoS One
Issue number11
Publication statusPublished - Nov 1 2018

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)


Dive into the research topics of 'Comparison among the available stone treatment techniques from the first European Association of Urology Section of Urolithiasis (EULIS) Survey: Do we have a queen?'. Together they form a unique fingerprint.

Cite this