Abstract
Introduction. Cryoballoon (CB) ablation has emerged as a novel treatment for pulmonary vein isolation (PVI) for patients with paroxysmal atrial fibrillation (PAF). The second-generation Arctic Front Advance (ADV) was redesigned with technical modifications aiming at procedural and outcome improvements. We aimed to compare the efficacy of the two different technologies over a long-term follow-up. Methods. A total of 120 patients with PAF were enrolled. Sixty patients underwent PVI using the first-generation CB and 60 patients with the ADV catheter. All patients were evaluated over a follow-up period of 2 years. Results. There were no significant differences between the two groups of patients. Procedures performed with the first-generation CB showed longer fluoroscopy time (36.3±16.8 versus 14.2±13.5 min, resp.; p=0.00016) and longer procedure times as well (153.1±32 versus 102±24.8 min, resp.; p=0.019). The overall long-term success was significantly different between the two groups (68.3 versus 86.7%, resp.; p=0.017). No differences were found in the lesion areas of left and right PV between the two groups (resp., p=0.61 and 0.57). There were no significant differences in procedural-related complications. Conclusion. The ADV catheter compared to the first-generation balloon allows obtaining a significantly higher success rate after a single PVI procedure during the long-term follow-up. Fluoroscopy and procedural times were significantly shortened using the ADV catheter.
| Original language | English |
|---|---|
| Article number | 5106127 |
| Journal | Cardiology Research and Practice |
| Volume | 2016 |
| DOIs | |
| Publication status | Published - 2016 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
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Comparison between First-and Second-Generation Cryoballoon for Paroxysmal Atrial Fibrillation Ablation. / Conti, Sergio; Moltrasio, Massimo; Fassini, Gaetano; Tundo, Fabrizio; Riva, Stefania; Dello Russo, Antonio; Casella, Michela; Majocchi, Benedetta; Marino, Vittoria; De Iuliis, Pasquale; Catto, Valentina Ilaria Maria; Pala, Salvatore; Tondo, Claudio.
In: Cardiology Research and Practice, Vol. 2016, 5106127, 2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison between First-and Second-Generation Cryoballoon for Paroxysmal Atrial Fibrillation Ablation
AU - Conti, Sergio
AU - Moltrasio, Massimo
AU - Fassini, Gaetano
AU - Tundo, Fabrizio
AU - Riva, Stefania
AU - Dello Russo, Antonio
AU - Casella, Michela
AU - Majocchi, Benedetta
AU - Marino, Vittoria
AU - De Iuliis, Pasquale
AU - Catto, Valentina Ilaria Maria
AU - Pala, Salvatore
AU - Tondo, Claudio
PY - 2016
Y1 - 2016
N2 - Introduction. Cryoballoon (CB) ablation has emerged as a novel treatment for pulmonary vein isolation (PVI) for patients with paroxysmal atrial fibrillation (PAF). The second-generation Arctic Front Advance (ADV) was redesigned with technical modifications aiming at procedural and outcome improvements. We aimed to compare the efficacy of the two different technologies over a long-term follow-up. Methods. A total of 120 patients with PAF were enrolled. Sixty patients underwent PVI using the first-generation CB and 60 patients with the ADV catheter. All patients were evaluated over a follow-up period of 2 years. Results. There were no significant differences between the two groups of patients. Procedures performed with the first-generation CB showed longer fluoroscopy time (36.3±16.8 versus 14.2±13.5 min, resp.; p=0.00016) and longer procedure times as well (153.1±32 versus 102±24.8 min, resp.; p=0.019). The overall long-term success was significantly different between the two groups (68.3 versus 86.7%, resp.; p=0.017). No differences were found in the lesion areas of left and right PV between the two groups (resp., p=0.61 and 0.57). There were no significant differences in procedural-related complications. Conclusion. The ADV catheter compared to the first-generation balloon allows obtaining a significantly higher success rate after a single PVI procedure during the long-term follow-up. Fluoroscopy and procedural times were significantly shortened using the ADV catheter.
AB - Introduction. Cryoballoon (CB) ablation has emerged as a novel treatment for pulmonary vein isolation (PVI) for patients with paroxysmal atrial fibrillation (PAF). The second-generation Arctic Front Advance (ADV) was redesigned with technical modifications aiming at procedural and outcome improvements. We aimed to compare the efficacy of the two different technologies over a long-term follow-up. Methods. A total of 120 patients with PAF were enrolled. Sixty patients underwent PVI using the first-generation CB and 60 patients with the ADV catheter. All patients were evaluated over a follow-up period of 2 years. Results. There were no significant differences between the two groups of patients. Procedures performed with the first-generation CB showed longer fluoroscopy time (36.3±16.8 versus 14.2±13.5 min, resp.; p=0.00016) and longer procedure times as well (153.1±32 versus 102±24.8 min, resp.; p=0.019). The overall long-term success was significantly different between the two groups (68.3 versus 86.7%, resp.; p=0.017). No differences were found in the lesion areas of left and right PV between the two groups (resp., p=0.61 and 0.57). There were no significant differences in procedural-related complications. Conclusion. The ADV catheter compared to the first-generation balloon allows obtaining a significantly higher success rate after a single PVI procedure during the long-term follow-up. Fluoroscopy and procedural times were significantly shortened using the ADV catheter.
UR - http://www.scopus.com/inward/record.url?scp=84962750593&partnerID=8YFLogxK
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U2 - 10.1155/2016/5106127
DO - 10.1155/2016/5106127
M3 - Article
AN - SCOPUS:84962750593
VL - 2016
JO - Cardiology Research and Practice
JF - Cardiology Research and Practice
SN - 2090-0597
M1 - 5106127
ER -