Comparison between gleason score and apparent diffusion coefficient obtained from diffusion-weighted imaging of prostate cancer patients

Rocchina Caivano; Paola Rabasco; Antonella Lotumolo; Patrizia Cirillo; Felice D'Antuono; Alexis Zandolino; Antonio Villonio; Luca Macarini; Marco Salvatore; Aldo Cammarota

doi:10.3109/07357907.2013.845673

Comparison between gleason score and apparent diffusion coefficient obtained from diffusion-weighted imaging of prostate cancer patients

Rocchina Caivano, Paola Rabasco, Antonella Lotumolo, Patrizia Cirillo, Felice D'Antuono, Alexis Zandolino, Antonio Villonio, Luca Macarini, Marco Salvatore, Aldo Cammarota

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: To correlate the apparent diffusion coefficient (ADC) of prostate cancer patients with pathological Gleason scores (GS). Methods: 40 patients with GS 2 + 3, 3 + 3, 3 + 4, or 4 + 4 were selected. The magnetic resonance imaging (MRI) study was performed adding axial diffusion-weighted imaging (DWI) sequences to the standard MRI protocol. ADC values obtained were correlated with the GS data. Results: Statistically significant differences of ADC (p <.05) were found among GS groups with a trend of decreasing ADC values with increasing GS. Conclusions: The ADC values may help clinicians to delineate prostate carcinoma, recognizing its high- or low-grade compartments.

Original language	English
Pages (from-to)	625-629
Number of pages	5
Journal	Cancer Investigation
Volume	31
Issue number	9
DOIs	https://doi.org/10.3109/07357907.2013.845673
Publication status	Published - Nov 2013

Keywords

ADC
Diffusion-weighted imaging
Gleason score
Magnetic resonance imaging
Prostate cancer

ASJC Scopus subject areas

Cancer Research
Oncology

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Caivano, R., Rabasco, P., Lotumolo, A., Cirillo, P., D'Antuono, F., Zandolino, A., Villonio, A., Macarini, L., Salvatore, M., & Cammarota, A. (2013). Comparison between gleason score and apparent diffusion coefficient obtained from diffusion-weighted imaging of prostate cancer patients. Cancer Investigation, 31(9), 625-629. https://doi.org/10.3109/07357907.2013.845673

Comparison between gleason score and apparent diffusion coefficient obtained from diffusion-weighted imaging of prostate cancer patients. / Caivano, Rocchina; Rabasco, Paola; Lotumolo, Antonella; Cirillo, Patrizia; D'Antuono, Felice; Zandolino, Alexis; Villonio, Antonio; Macarini, Luca; Salvatore, Marco; Cammarota, Aldo.

In: Cancer Investigation, Vol. 31, No. 9, 11.2013, p. 625-629.

Research output: Contribution to journal › Article › peer-review

Caivano, R, Rabasco, P, Lotumolo, A, Cirillo, P, D'Antuono, F, Zandolino, A, Villonio, A, Macarini, L, Salvatore, M & Cammarota, A 2013, 'Comparison between gleason score and apparent diffusion coefficient obtained from diffusion-weighted imaging of prostate cancer patients', Cancer Investigation, vol. 31, no. 9, pp. 625-629. https://doi.org/10.3109/07357907.2013.845673

Caivano, Rocchina ; Rabasco, Paola ; Lotumolo, Antonella ; Cirillo, Patrizia ; D'Antuono, Felice ; Zandolino, Alexis ; Villonio, Antonio ; Macarini, Luca ; Salvatore, Marco ; Cammarota, Aldo. / Comparison between gleason score and apparent diffusion coefficient obtained from diffusion-weighted imaging of prostate cancer patients. In: Cancer Investigation. 2013 ; Vol. 31, No. 9. pp. 625-629.

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abstract = "Objectives: To correlate the apparent diffusion coefficient (ADC) of prostate cancer patients with pathological Gleason scores (GS). Methods: 40 patients with GS 2 + 3, 3 + 3, 3 + 4, or 4 + 4 were selected. The magnetic resonance imaging (MRI) study was performed adding axial diffusion-weighted imaging (DWI) sequences to the standard MRI protocol. ADC values obtained were correlated with the GS data. Results: Statistically significant differences of ADC (p <.05) were found among GS groups with a trend of decreasing ADC values with increasing GS. Conclusions: The ADC values may help clinicians to delineate prostate carcinoma, recognizing its high- or low-grade compartments.",

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author = "Rocchina Caivano and Paola Rabasco and Antonella Lotumolo and Patrizia Cirillo and Felice D'Antuono and Alexis Zandolino and Antonio Villonio and Luca Macarini and Marco Salvatore and Aldo Cammarota",

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AU - D'Antuono, Felice

AU - Zandolino, Alexis

AU - Villonio, Antonio

AU - Macarini, Luca

AU - Salvatore, Marco

AU - Cammarota, Aldo

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