Abstract
Objectives: To correlate the apparent diffusion coefficient (ADC) of prostate cancer patients with pathological Gleason scores (GS). Methods: 40 patients with GS 2 + 3, 3 + 3, 3 + 4, or 4 + 4 were selected. The magnetic resonance imaging (MRI) study was performed adding axial diffusion-weighted imaging (DWI) sequences to the standard MRI protocol. ADC values obtained were correlated with the GS data. Results: Statistically significant differences of ADC (p <.05) were found among GS groups with a trend of decreasing ADC values with increasing GS. Conclusions: The ADC values may help clinicians to delineate prostate carcinoma, recognizing its high- or low-grade compartments.
Original language | English |
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Pages (from-to) | 625-629 |
Number of pages | 5 |
Journal | Cancer Investigation |
Volume | 31 |
Issue number | 9 |
DOIs | |
Publication status | Published - Nov 2013 |
Keywords
- ADC
- Diffusion-weighted imaging
- Gleason score
- Magnetic resonance imaging
- Prostate cancer
ASJC Scopus subject areas
- Cancer Research
- Oncology