Comparison between lidocaine-prilocaine cream (EMLA) and mepivacaine infiltration for pain relief during perineal repair after childbirth: a randomized trial

Massimo Franchi, Antonella Cromi, Stefano Scarperi, Francesca Gaudino, Gabriele Siesto, Fabio Ghezzi

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The purpose of this study was to compare the effectiveness of topically applied lidocaine-prilocaine (EMLA) cream with local anesthetic infiltration in the reduction of pain during perineal suturing after childbirth. Study Design: Sixty-one women with either an episiotomy or a perineal laceration after vaginal delivery were assigned randomly to receive either the application of EMLA cream (n = 31) or infiltration with mepivacaine (n = 30) before perineal suturing. Primary outcome was pain during perineal repair. Results: Women in the EMLA group had lower pain scores than those in the mepivacaine group (1.7 ± 2.4 vs 3.9 ± 2.4; P = .0002). The proportion of women who needed additional anesthesia was similar in the 2 groups (3/30 vs 5/31; P = .71). A significantly higher proportion of women expressed satisfaction with anesthesia method in the EMLA group, compared with the mepivacaine group (83.8% vs 53.3%; P = .01). Conclusion: EMLA cream appears to be an effective and satisfactory alternative to local anesthetic infiltration for the relief of pain during perineal repair.

Original languageEnglish
JournalAmerican Journal of Obstetrics and Gynecology
Volume201
Issue number2
DOIs
Publication statusPublished - Aug 2009

Keywords

  • EMLA
  • lidocaine-prilocaine cream
  • pain
  • perineal suturing
  • vaginal delivery

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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