Comparison between surgery and radiotherapy in the treatment of stage Ib and II proximal cervical cancer

F. Volterrani, L. Lozza, S. Tana, N. Di Muzio

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Radiotherapy alone or radical surgery and different radio-surgical combinations in the treatment of invasive cervical cancer are still a topic for discussion. The purpose of the study was to compare the results achieved respectively with radiotherapy alone and primary surgery in 572 consecutive and unselected cases of Stage Ib-II proximal cervical cancer treated in the years 1971/85.327 patients (57.2%) were submitted to surgery. Following the operation intracavitary curietherapy was usually performed on the vault of the vaginal stump. In 28/40 (49.0%) N+ cases a complete course of pelvic + lumbarortic RT was performed (45-50 Gy in 5-6 weeks). 245 patients were treated with radiotherapy alone. Five and 10-year relapse free survival (RFS) was respectively 86.8% and 78.0% for the group submitted to surgery + postoperative radiotherapy, 81.3% and 75.0% for the group treated with radiotherapy alone. The results of surgery and radiotherapy substantially coincided for stage Ib (5-year RFS respectively 86.6% and 86.4%). On the contrary, for stage II proximal the best results were observed for the surgical group (5-year RFS 81.5% vs. 68.6%). In recent years radiotherapy of cervical cancer has been considerably renewed with the modern radium substitutes. Stage II proximal cases have benefitted from the improved irradiation techniques. For the patients treated with radiotherapy alone, 5-year RFS was 64.2% for the group treated in the years 1971/79 against 81.4% observed for the cases treated in the period 1980/85.

Original languageEnglish
Pages (from-to)99-110
Number of pages12
JournalCervix and the Lower Female Genital Tract
Issue number1
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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