Comparison between the in vitro surface transformations of AP40 and RKKP bioactive glasses

A. Krajewski, A. Ravaglioli, A. Tinti, P. Taddei, M. Mazzocchi, R. Martinetti, C. Fagnano, M. Fini

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Two bioactive silica-phosphate glasses, AP40 and RKKP, were compared in their behaviour in simulated biological environment. Their chemical composition is practically identical, except that RKKP contains small amounts of amphoteric network-former oxides Ta2O5 and La2O 3 (composition in wt% for AP40: β-Ca3(PO 4)224.50, SiO244.30, CaO 18.60, Na2O 4.60, K2O 0.19, MgO 2.82, CaF2 4.99; RKKP: β-Ca 3(PO4)224.23, SiO2 43.82, CaO 18.40, Na2O 4.55, K2O 0.19, MgO 2.79, CaF2 4.94, Ta2O5 0.99, La2O3 0.09). Previous investigations showed a better performance in osteopenic bone for RKKP. To gain more insight into these differences in biological behaviour, the in vitro bioactivity of the glasses was studied by treatment with a continuously replenished Hanks' Balanced Salt Solution (HBSS). The glasses were examined before and after HBSS treatment for 20 and 40 days by X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), X-ray Energy Dispersion (EDX), Raman and IR vibrational spectroscopies. Some slight but notable differences between the two glasses were observed after HBSS treatment. IR and EDX analyses showed that deposits formed on both glasses were composed of a calcium deficient carbonate-apatite; however, the layer formed on RKKP glass was found to be slightly more calcium deficient and thinner. EDX analysis evidenced the presence of a small percentage of F- ions only in the layers formed on the RKKP samples. The differences disclosed, although slight, can contribute to the understanding of the different biological behaviour previously observed.

Original languageEnglish
Pages (from-to)119-128
Number of pages10
JournalJournal of Materials Science: Materials in Medicine
Volume16
Issue number2
DOIs
Publication statusPublished - Feb 2005

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Bioactive glass
Glass
Energy dispersive spectroscopy
Salts
Vibrational spectroscopy
Apatite
Calcium carbonate
Bioactivity
Chemical analysis
bio-vitroceramic AP40
In Vitro Techniques
Calcium Carbonate
Infrared spectroscopy
Calcium
Bone
Phosphates
Deposits
Silica
X-Ray Diffraction
Silicon Dioxide

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Chemical Engineering(all)

Cite this

Comparison between the in vitro surface transformations of AP40 and RKKP bioactive glasses. / Krajewski, A.; Ravaglioli, A.; Tinti, A.; Taddei, P.; Mazzocchi, M.; Martinetti, R.; Fagnano, C.; Fini, M.

In: Journal of Materials Science: Materials in Medicine, Vol. 16, No. 2, 02.2005, p. 119-128.

Research output: Contribution to journalArticle

Krajewski, A, Ravaglioli, A, Tinti, A, Taddei, P, Mazzocchi, M, Martinetti, R, Fagnano, C & Fini, M 2005, 'Comparison between the in vitro surface transformations of AP40 and RKKP bioactive glasses', Journal of Materials Science: Materials in Medicine, vol. 16, no. 2, pp. 119-128. https://doi.org/10.1007/s10856-005-5913-y
Krajewski, A. ; Ravaglioli, A. ; Tinti, A. ; Taddei, P. ; Mazzocchi, M. ; Martinetti, R. ; Fagnano, C. ; Fini, M. / Comparison between the in vitro surface transformations of AP40 and RKKP bioactive glasses. In: Journal of Materials Science: Materials in Medicine. 2005 ; Vol. 16, No. 2. pp. 119-128.
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