Confronto tra due metodi per la misura nel siero della proteina 4 dell'epididimo umano (HE4) nella diagnosi di carcinoma ovarico

Translated title of the contribution: Comparison between two methods for the determination of serum human epididymis protein 4 (HE4) in the diagnosis of ovarian cancer

Antonette E. Leon, Elisa Squarcina, Tiziano Maggino, Cesare Romagnolo, Lino Del Pup, Silvia Cervo, Massimo Gion, Aline S C Fabricio

Research output: Contribution to journalArticle

Abstract

Analytical performance and diagnostic accuracy of two commercial immunoassays for the determination of HE4 in the diagnosis of ovarian cancer were evaluated. HE4 was determined on sera consecutively obtained from 205 women (163 with benign ovarian or adnexal disease and 42 with ovarian cancer) by using a manual EIA (Fujirebio Diagnostics, Inc.) and an automated chemiluminescent microparticle assay (CMIA) (Abbott Architect platform). The intra- and interassay imprecision for EIA and CMIA was satisfactory (CV

Original languageItalian
Pages (from-to)200-207
Number of pages8
JournalBiochimica Clinica
Volume37
Issue number3
Publication statusPublished - Jun 2013

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Luminescent Measurements
Epididymis
Ovarian Neoplasms
Adnexal Diseases
Assays
Ovarian Diseases
Serum
Immunoassay
Proteins

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical
  • Medical Laboratory Technology

Cite this

Leon, A. E., Squarcina, E., Maggino, T., Romagnolo, C., Del Pup, L., Cervo, S., ... Fabricio, A. S. C. (2013). Confronto tra due metodi per la misura nel siero della proteina 4 dell'epididimo umano (HE4) nella diagnosi di carcinoma ovarico. Biochimica Clinica, 37(3), 200-207.

Confronto tra due metodi per la misura nel siero della proteina 4 dell'epididimo umano (HE4) nella diagnosi di carcinoma ovarico. / Leon, Antonette E.; Squarcina, Elisa; Maggino, Tiziano; Romagnolo, Cesare; Del Pup, Lino; Cervo, Silvia; Gion, Massimo; Fabricio, Aline S C.

In: Biochimica Clinica, Vol. 37, No. 3, 06.2013, p. 200-207.

Research output: Contribution to journalArticle

Leon, AE, Squarcina, E, Maggino, T, Romagnolo, C, Del Pup, L, Cervo, S, Gion, M & Fabricio, ASC 2013, 'Confronto tra due metodi per la misura nel siero della proteina 4 dell'epididimo umano (HE4) nella diagnosi di carcinoma ovarico', Biochimica Clinica, vol. 37, no. 3, pp. 200-207.
Leon AE, Squarcina E, Maggino T, Romagnolo C, Del Pup L, Cervo S et al. Confronto tra due metodi per la misura nel siero della proteina 4 dell'epididimo umano (HE4) nella diagnosi di carcinoma ovarico. Biochimica Clinica. 2013 Jun;37(3):200-207.
Leon, Antonette E. ; Squarcina, Elisa ; Maggino, Tiziano ; Romagnolo, Cesare ; Del Pup, Lino ; Cervo, Silvia ; Gion, Massimo ; Fabricio, Aline S C. / Confronto tra due metodi per la misura nel siero della proteina 4 dell'epididimo umano (HE4) nella diagnosi di carcinoma ovarico. In: Biochimica Clinica. 2013 ; Vol. 37, No. 3. pp. 200-207.
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