Comparison of anterior segment measurements obtained using a swept-source optical coherence tomography biometer and a Scheimpflug–Placido tomographer

Weicong Lu, Yue Li, Giacomo Savini, Benhao Song, Qingjie Hu, Qinmei Wang, Fangjun Bao, Jinhai Huang

Research output: Contribution to journalArticle

Abstract

Purpose: To assess the repeatability and agreement of anterior segment measurements between an optical biometer (IOLMaster 700) using swept-source optical coherence tomography and a Scheimpflug–Placido tomographer (Sirius) in patients scheduled for corneal refractive surgery. Setting: Eye Hospital of Wenzhou Medical University, Zhejiang, China. Design: Prospective case series. Methods: The parameters, including the central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, keratometry (K) values, astigmatism, J0 (Jackson cross-cylinder with axes at 180 degree and 90 degrees) and J45 vectors (Jackson cross-cylinder with axes at 45 degrees and 135 degrees), and horizontal corneal diameter, were measured 3 times per instrument. The intraobserver repeatability was assessed using test–retest repeatability, the coefficient of variation (CoV), and the intraclass correlation coefficient (ICC). Paired t tests were used to compare the difference between the 2 methods. Agreement was evaluated using Bland-Altman analyses. Results: The study enrolled 100 right eyes. All measurements of the 2 devices showed high repeatability. The CoV of all measured parameters was less than 0.93 and the ICC value was more than 0.85. The paired t test did not show a significant difference in CCT, astigmatism, J0 or J45 vector. The mean ACD and aqueous depth were statistically lower with the optical biometer; however, the 95% limits of agreement (LoA) were low (from −0.20 to −0.03 mm). The K and corneal diameter values obtained using the optical biometer were higher by 0.1 diopter and 0.1 mm, respectively, but with narrow 95% LoA. Conclusions: The optical biometer and the Scheimpflug–Placido tomographer showed high repeatability for all anterior segment measurements. The measured parameters showed good agreement and could be used interchangeably.

Original languageEnglish
Pages (from-to)298-304
Number of pages7
JournalJournal of Cataract and Refractive Surgery
Volume45
Issue number3
DOIs
Publication statusPublished - Mar 2019

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems

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