Comparison of effectiveness of carvedilol versus bisoprolol for prevention of postdischarge atrial fibrillation after coronary artery bypass grafting in patients with heart failure

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Abstract

Atrial fibrillation (AF) occurs frequently soon after coronary artery bypass grafting (CABG) and often results in increased mortality and morbidity, particularly in patients with heart failure. New-onset AF is also a common event in the early period after discharge from a cardiac surgery clinic. Current guidelines recommend β blockers as first-line medication for the prevention of AF after CABG. In this prospective study, we investigated the effectiveness of the highly selective β1 receptor antagonist bisoprolol compared to the less selective β blocker carvedilol in preventing postdischarge AF after CABG in patients with decreased left ventricular function. Three hundred twenty patients (231 men, 89 women, mean age 66 ± 10 years) with ejection fraction

Original languageEnglish
Pages (from-to)215-219
Number of pages5
JournalThe American Journal of Cardiology
Volume107
Issue number2
DOIs
Publication statusPublished - Jan 15 2011

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Bisoprolol
Coronary Artery Bypass
Atrial Fibrillation
Heart Failure
Left Ventricular Function
Thoracic Surgery
Prospective Studies
Guidelines
Morbidity
Mortality
carvedilol

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

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title = "Comparison of effectiveness of carvedilol versus bisoprolol for prevention of postdischarge atrial fibrillation after coronary artery bypass grafting in patients with heart failure",
abstract = "Atrial fibrillation (AF) occurs frequently soon after coronary artery bypass grafting (CABG) and often results in increased mortality and morbidity, particularly in patients with heart failure. New-onset AF is also a common event in the early period after discharge from a cardiac surgery clinic. Current guidelines recommend β blockers as first-line medication for the prevention of AF after CABG. In this prospective study, we investigated the effectiveness of the highly selective β1 receptor antagonist bisoprolol compared to the less selective β blocker carvedilol in preventing postdischarge AF after CABG in patients with decreased left ventricular function. Three hundred twenty patients (231 men, 89 women, mean age 66 ± 10 years) with ejection fraction",
author = "Giuseppe Marazzi and Ferdinando Iellamo and Maurizio Volterrani and Giuseppe Caminiti and Mariapina Madonna and Giovanna Arisi and Rosalba Massaro and Daniela Righi and Rosano, {Giuseppe M C}",
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T1 - Comparison of effectiveness of carvedilol versus bisoprolol for prevention of postdischarge atrial fibrillation after coronary artery bypass grafting in patients with heart failure

AU - Marazzi, Giuseppe

AU - Iellamo, Ferdinando

AU - Volterrani, Maurizio

AU - Caminiti, Giuseppe

AU - Madonna, Mariapina

AU - Arisi, Giovanna

AU - Massaro, Rosalba

AU - Righi, Daniela

AU - Rosano, Giuseppe M C

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