Comparison of functional recovery of mildly hypokinetic versus severely dysfunctional left ventricular segments after revascularization in patients with ischemic cardiomyopathy

Vittoria Rizzello, Elena Biagini, Arend F L Schinkel, Manolis Bountioukos, Eric Boersma, Eleni C. Vourvouri, Fabiola B. Sozzi, Abdou Elhendy, Jos R T C Roelandt, Don Poldermans, Jeroen J. Bax

Research output: Contribution to journalArticle

Abstract

Dysfunctional left ventricular (LV) segments showing contractile reserve during dobutamine stress echocardiography (DSE) are considered viable myocardium; functional recovery is expected after revascularization. Many segments, however, particularly mildly hypokinetic segments, do not recover. The reason for this failure is unknown. Two-dimensional echocardiography at rest and low-high-dose DSE were performed before revascularization in 114 consecutive patients with ischemic cardiomyopathy. Two-dimensional echocardiography at rest was repeated after 9 to 12 months. Segmental function was scored by a 5-point grading score. Functional recovery after revascularization was assessed in mildly hypokinetic (score 2, group I) and severely dysfunctional segments (score 3 to 5, group II). For each segment, functional recovery was defined as an improvement in functional score of ≥1 grade compared with the baseline score at rest. During low-dose DSE (up to 10 μg/kg/min), 183 group I segments (68%) and 438 group II (39%) segments had contractile reserve (p

Original languageEnglish
Pages (from-to)394-398
Number of pages5
JournalThe American Journal of Cardiology
Volume93
Issue number4
DOIs
Publication statusPublished - Feb 15 2004

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Stress Echocardiography
Cardiomyopathies
Echocardiography
Myocardium

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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Comparison of functional recovery of mildly hypokinetic versus severely dysfunctional left ventricular segments after revascularization in patients with ischemic cardiomyopathy. / Rizzello, Vittoria; Biagini, Elena; Schinkel, Arend F L; Bountioukos, Manolis; Boersma, Eric; Vourvouri, Eleni C.; Sozzi, Fabiola B.; Elhendy, Abdou; Roelandt, Jos R T C; Poldermans, Don; Bax, Jeroen J.

In: The American Journal of Cardiology, Vol. 93, No. 4, 15.02.2004, p. 394-398.

Research output: Contribution to journalArticle

Rizzello, Vittoria ; Biagini, Elena ; Schinkel, Arend F L ; Bountioukos, Manolis ; Boersma, Eric ; Vourvouri, Eleni C. ; Sozzi, Fabiola B. ; Elhendy, Abdou ; Roelandt, Jos R T C ; Poldermans, Don ; Bax, Jeroen J. / Comparison of functional recovery of mildly hypokinetic versus severely dysfunctional left ventricular segments after revascularization in patients with ischemic cardiomyopathy. In: The American Journal of Cardiology. 2004 ; Vol. 93, No. 4. pp. 394-398.
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