Comparison of functional recovery of mildly hypokinetic versus severely dysfunctional left ventricular segments after revascularization in patients with ischemic cardiomyopathy

Vittoria Rizzello, Elena Biagini, Arend F L Schinkel, Manolis Bountioukos, Eric Boersma, Eleni C. Vourvouri, Fabiola B. Sozzi, Abdou Elhendy, Jos R T C Roelandt, Don Poldermans, Jeroen J. Bax

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Abstract

Dysfunctional left ventricular (LV) segments showing contractile reserve during dobutamine stress echocardiography (DSE) are considered viable myocardium; functional recovery is expected after revascularization. Many segments, however, particularly mildly hypokinetic segments, do not recover. The reason for this failure is unknown. Two-dimensional echocardiography at rest and low-high-dose DSE were performed before revascularization in 114 consecutive patients with ischemic cardiomyopathy. Two-dimensional echocardiography at rest was repeated after 9 to 12 months. Segmental function was scored by a 5-point grading score. Functional recovery after revascularization was assessed in mildly hypokinetic (score 2, group I) and severely dysfunctional segments (score 3 to 5, group II). For each segment, functional recovery was defined as an improvement in functional score of ≥1 grade compared with the baseline score at rest. During low-dose DSE (up to 10 μg/kg/min), 183 group I segments (68%) and 438 group II (39%) segments had contractile reserve (p

Original languageEnglish
Pages (from-to)394-398
Number of pages5
JournalThe American Journal of Cardiology
Volume93
Issue number4
DOIs
Publication statusPublished - Feb 15 2004

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Rizzello, V., Biagini, E., Schinkel, A. F. L., Bountioukos, M., Boersma, E., Vourvouri, E. C., Sozzi, F. B., Elhendy, A., Roelandt, J. R. T. C., Poldermans, D., & Bax, J. J. (2004). Comparison of functional recovery of mildly hypokinetic versus severely dysfunctional left ventricular segments after revascularization in patients with ischemic cardiomyopathy. The American Journal of Cardiology, 93(4), 394-398. https://doi.org/10.1016/j.amjcard.2003.10.030