Comparison of optic nerve head parameter measurements obtained by time-domain and spectral-domain optical coherence tomography

Giacomo Savini, Piero Barboni, Michele Carbonelli, Alessandra Sbreglia, Giulia Deluigi, Vincenzo Parisi

Research output: Contribution to journalArticle


Purpose: To compare the measurements of the optic nerve head (ONH) parameters provided by time-domain (TD) and spectraldomain (SD) optical coherence tomography (OCT). Methods: Four ONH parameters were analyzed: optic disc area, rim area, cup-to-disc area ratio (CDR), and vertical cup-to-disc ratio (VCDR). Stratus OCT and Cirrus HD-OCT were used to obtain measurements by TD-OCT and SD-OCT, respectively. Stratus OCT measurements were collected before and after manual correction of the ONH edges. Results: Twenty healthy participants and 20 patients with glaucomatous eyes were enrolled. Although manual correction of Stratus OCT measurements reduced the differences compared with Cirrus HD-OCT, the latter measured a smaller mean disc area than Stratus OCT in healthy (2.02±0.31 vs. 2.18±0.29mm2, P=0.0003) and glaucomatous eyes (1.92±0.35 vs. 2.19± 0.38mm2, P2, P2, P=0.0052), a higher CDR (0.55±0.11 vs. 0.49±0.11, P

Original languageEnglish
Pages (from-to)384-389
Number of pages6
JournalJournal of Glaucoma
Issue number5
Publication statusPublished - Jun 2013



  • Glaucoma
  • Optic nerve
  • Optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology

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