Comparison of serum specific IgE and skin prick test in polysensitized children

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Background: Skin prick test (SPT) and serum specific IgE (ssIgE) measurements are the most common methods used to diagnose allergy. The aim of this study was to evaluate serum specific-IgE in a large group of polysensitized patients with the same SPT result (such as ++++) comparing the two diagnostic methods. Methods: Four hundred ninety-four children (310 males; median age 10 years) suffering from allergic rhinitis were studied. Serum specific-IgE values were measured by ImmunoCap assay. Skin prick test was also performed. Results: There was a significant difference (p <0.0001) among serum specific-IgE values in these polysensitized patients. Conclusions: The ss-IgE measurements in polysensitized patients seem to be more appropriate than SPT.

Original languageEnglish
Pages (from-to)83-85
Number of pages3
JournalClinical Laboratory
Issue number1-2
Publication statusPublished - 2011

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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