Comparison of the performance of different silicon-based SALDI substrates for illicit drug detection

T. Guinan; M. Ronci; R. Vasani; H. Kobus; N. H. Voelcker

doi:10.1016/j.talanta.2014.09.040

Comparison of the performance of different silicon-based SALDI substrates for illicit drug detection

T. Guinan, M. Ronci, R. Vasani, H. Kobus, N. H. Voelcker

Fondazione Santa Lucia

Research output: Contribution to journal › Article › peer-review

Abstract

Surface-assisted laser desorption ionization mass spectrometry (SALDI-MS) is an emerging technique used for the detection of small molecules (™) are compared for the detection of four drug classes, amphetamines, benzodiazepines, opiates and tropane alkaloids. We focus in our comparison on structural and chemical characteristics, as well as analytical performance and longevity.

Original language	English
Pages (from-to)	494-502
Number of pages	9
Journal	Talanta
Volume	132
DOIs	https://doi.org/10.1016/j.talanta.2014.09.040
Publication status	Published - Jan 15 2015

Keywords

DIOS
Drug detection
NALDI
NIMS
SALDI

ASJC Scopus subject areas

Chemistry(all)
Medicine(all)

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abstract = "Surface-assisted laser desorption ionization mass spectrometry (SALDI-MS) is an emerging technique used for the detection of small molecules ({\texttrademark}) are compared for the detection of four drug classes, amphetamines, benzodiazepines, opiates and tropane alkaloids. We focus in our comparison on structural and chemical characteristics, as well as analytical performance and longevity.",

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AU - Guinan, T.

AU - Ronci, M.

AU - Vasani, R.

AU - Kobus, H.

AU - Voelcker, N. H.

PY - 2015/1/15

Y1 - 2015/1/15

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AB - Surface-assisted laser desorption ionization mass spectrometry (SALDI-MS) is an emerging technique used for the detection of small molecules (™) are compared for the detection of four drug classes, amphetamines, benzodiazepines, opiates and tropane alkaloids. We focus in our comparison on structural and chemical characteristics, as well as analytical performance and longevity.

KW - DIOS

KW - Drug detection

KW - NALDI

KW - NIMS

KW - SALDI

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JO - Talanta

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ER -

Comparison of the performance of different silicon-based SALDI substrates for illicit drug detection

Abstract

Keywords

ASJC Scopus subject areas

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