Abstract
The Combination of Avodart and Tamsulosin study was a 4-year, randomized, double-blind study of the efficacy and safety of dutasteride and tamsulosin, alone or in combination, in men with moderate-to-severe benign prostatic hyperplasia. In this post-hoc investigation, we analyzed primary and secondary end-points from the Combination of Avodart and Tamsulosin study in Asian (n=325) and Caucasian men (n=4259). The incidence of acute urinary retention or benign prostatic hyperplasia-related surgery did not differ significantly between treatment groups in the Asian subpopulation. In Caucasian men, the incidence of acute urinary retention/benign prostatic hyperplasia-related surgery was significantly lower in the combination therapy group compared with the tamsulosin monotherapy group (P
Original language | English |
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Pages (from-to) | 1031-1035 |
Number of pages | 5 |
Journal | International Journal of Urology |
Volume | 19 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2012 |
Keywords
- Asian
- Benign prostatic hyperplasia
- Caucasian
- Dutasteride
- Tamsulosin
ASJC Scopus subject areas
- Urology