Comparison of the response to treatment between Asian and Caucasian men with benign prostatic hyperplasia: Long-term results from the combination of dutasteride and tamsulosin study

Byung Ha Chung, Seung Hwan Lee, Claus G. Roehrborn, Paul F. Siami, Kim Major-Walker, Timothy H. Wilson, Francesco Montorsi

Research output: Contribution to journalArticlepeer-review

Abstract

The Combination of Avodart and Tamsulosin study was a 4-year, randomized, double-blind study of the efficacy and safety of dutasteride and tamsulosin, alone or in combination, in men with moderate-to-severe benign prostatic hyperplasia. In this post-hoc investigation, we analyzed primary and secondary end-points from the Combination of Avodart and Tamsulosin study in Asian (n=325) and Caucasian men (n=4259). The incidence of acute urinary retention or benign prostatic hyperplasia-related surgery did not differ significantly between treatment groups in the Asian subpopulation. In Caucasian men, the incidence of acute urinary retention/benign prostatic hyperplasia-related surgery was significantly lower in the combination therapy group compared with the tamsulosin monotherapy group (P

Original languageEnglish
Pages (from-to)1031-1035
Number of pages5
JournalInternational Journal of Urology
Volume19
Issue number11
DOIs
Publication statusPublished - Nov 2012

Keywords

  • Asian
  • Benign prostatic hyperplasia
  • Caucasian
  • Dutasteride
  • Tamsulosin

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Comparison of the response to treatment between Asian and Caucasian men with benign prostatic hyperplasia: Long-term results from the combination of dutasteride and tamsulosin study'. Together they form a unique fingerprint.

Cite this