Comparison of two models for the prediction of nonsentinel node metastases in breast cancer

Riccardo Ponzone, Furio Maggiorotto, Luca Mariani, Maria Elena Jacomuzzi, Alessandra Magistris, Paola Mininanni, Nicoletta Biglia, Piero Sismondi

Research output: Contribution to journalArticle

Abstract

Background: It is debated whether all patients with a positive sentinel node dissection (SLND) should be submitted to axillary lymph node dissection (ALND). Models have been developed to estimate the likelihood of nonsentinel node (non-SLN) metastases. Methods: The accuracy of the Memorial Sloan-Kettering Cancer Center (MSKCC) nomogram and MD Anderson scoring system for the prediction of non-SLN status was tested in a consecutive series of 186 SLN-positive breast cancer patients. A multivariate analysis was performed to assess which parameters independently predicted the presence of non-SLN metastases. Results: The predictive accuracy of the MSKCC nomogram measured by the receiver operating characteristic curve was 0.71, and it was best in patients with

Original languageEnglish
Pages (from-to)686-692
Number of pages7
JournalAmerican Journal of Surgery
Volume193
Issue number6
DOIs
Publication statusPublished - Jun 2007

Keywords

  • Breast cancer
  • Metastases
  • Nomogram
  • Score
  • Sentinel node

ASJC Scopus subject areas

  • Surgery

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