Compensation of labyrinthine lesions: Effects of trigeminal neurotomy on vestibular field potentials

L. Petrosini, D. Troiani, B. Zannoni

Research output: Contribution to journalArticle

Abstract

The aim of the research was to analyse the vestibular nuclear activity before and after the section of the 5th cranial nerve in chronically hemilabyrinthectomized guinea pigs during the stage of compensation. The animals were hemilabyrinthectomized (chloroform and vaselin oil into the right middle ear) and upon compensation (24-45 days), field potentials were recorded from the vestibular nuclei of the intact side following electrical stimulation of the ipsilateral labyrinthine receptors. Then the left trigeminal trunk was sectioned ventrally through the foramen lacerum and ovale which are fused in the guinea pig and the vestibular field potentials were again recorded for a period of 120 min. Trigeminal neurotomy modified the vestibular field potentials determining an increment in amplitude of 30-50% of N1 and N2 waves, configuration and latency remained unaltered. The dependence of vestibular compensation on trigeminal afferents is discussed on the light of reported results.

Original languageEnglish
Pages (from-to)785-789
Number of pages5
JournalPhysiology and Behavior
Volume23
Issue number4
DOIs
Publication statusPublished - 1979

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Keywords

  • Trigeminal neurotomy
  • Vestibular compensation
  • Vestibular field potentials

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

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