Complement-mediated binding of immunoglobulins to some endocrine cells of the pancreas and gut

R. Buffa; E. Solcia; R. Fiocca; O. Crivelli; A. Pera

Complement-mediated binding of immunoglobulins to some endocrine cells of the pancreas and gut

R. Buffa, E. Solcia, R. Fiocca, O. Crivelli, A. Pera

Research output: Contribution to journal › Article › peer-review

Abstract

Unspecific binding of immunoglobulins to gastrin, somatostatin and glucagon cells of the gastrointestinal mucosa or pancreas has been found to occur through a nonantigen-antibody mechanism mediated by the C(1q)fraction of complement. The phenomenon represents an important drawback in hormone immunohistochemistry, which can be overcome by using complement deprived, highly dilute anti-hormone sera.

Original language	English
Pages (from-to)	1279-1280
Number of pages	2
Journal	Journal of Histochemistry and Cytochemistry
Volume	27
Issue number	9
Publication status	Published - 1979

ASJC Scopus subject areas

Anatomy
Cell Biology

Cite this

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title = "Complement-mediated binding of immunoglobulins to some endocrine cells of the pancreas and gut",

abstract = "Unspecific binding of immunoglobulins to gastrin, somatostatin and glucagon cells of the gastrointestinal mucosa or pancreas has been found to occur through a nonantigen-antibody mechanism mediated by the C(1q)fraction of complement. The phenomenon represents an important drawback in hormone immunohistochemistry, which can be overcome by using complement deprived, highly dilute anti-hormone sera.",

author = "R. Buffa and E. Solcia and R. Fiocca and O. Crivelli and A. Pera",

year = "1979",

language = "English",

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T1 - Complement-mediated binding of immunoglobulins to some endocrine cells of the pancreas and gut

AU - Buffa, R.

AU - Solcia, E.

AU - Fiocca, R.

AU - Crivelli, O.

AU - Pera, A.

PY - 1979

Y1 - 1979

N2 - Unspecific binding of immunoglobulins to gastrin, somatostatin and glucagon cells of the gastrointestinal mucosa or pancreas has been found to occur through a nonantigen-antibody mechanism mediated by the C(1q)fraction of complement. The phenomenon represents an important drawback in hormone immunohistochemistry, which can be overcome by using complement deprived, highly dilute anti-hormone sera.

AB - Unspecific binding of immunoglobulins to gastrin, somatostatin and glucagon cells of the gastrointestinal mucosa or pancreas has been found to occur through a nonantigen-antibody mechanism mediated by the C(1q)fraction of complement. The phenomenon represents an important drawback in hormone immunohistochemistry, which can be overcome by using complement deprived, highly dilute anti-hormone sera.

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AN - SCOPUS:0018729347

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JO - Journal of Histochemistry and Cytochemistry

JF - Journal of Histochemistry and Cytochemistry

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ER -

Complement-mediated binding of immunoglobulins to some endocrine cells of the pancreas and gut

Abstract

ASJC Scopus subject areas

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