Abstract
Unspecific binding of immunoglobulins to gastrin, somatostatin and glucagon cells of the gastrointestinal mucosa or pancreas has been found to occur through a nonantigen-antibody mechanism mediated by the C(1q)fraction of complement. The phenomenon represents an important drawback in hormone immunohistochemistry, which can be overcome by using complement deprived, highly dilute anti-hormone sera.
Original language | English |
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Pages (from-to) | 1279-1280 |
Number of pages | 2 |
Journal | Journal of Histochemistry and Cytochemistry |
Volume | 27 |
Issue number | 9 |
Publication status | Published - 1979 |
ASJC Scopus subject areas
- Anatomy
- Cell Biology