Two patients with primary plasma cell leukaemia who achieved complete remission are reported. They were treated with induction therapy consisting of a multipeptide derivative of sarcolysin, Peptichemio, given intravenously, combined with vincristine and/or prednisone, followed by conventional melphalan-prednisone therapy. 5-7 months following the beginning of therapy, both patients attained a complete remission which lasted 23 and 6 months; second remission was not achieved. Survival from starting therapy was 57 and 16 months respectively. These cases indicate that intravenously alkylating agents can induce a complete remission in plasma cell leukaemia similar to that achieved in other acute leukaemias.
|Number of pages||3|
|Journal||British Journal of Haematology|
|Publication status||Published - 1986|
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