Translated title of the contribution: Complex partial epilepsy: Etiologic, clinical and evolutive aspects

P. Pazzaglia, G. Ambrosetto, A. Forti, P. Giovanardi Rossi, G. Gobbi, R. Moschen, T. Sacquegna, E. Lugaresi

Research output: Contribution to journalArticlepeer-review


The authors studied 206 patients who presented partial complex seizures (PCS). These patients were observed from 1973-75 at the Centro dell'Epilessia della Clinica Neurologica dell'Universita di Bologna, and, during this period partial complex epilepsy (PCE) partial complex epilepsy (PCE) represented about 1/3 of all epilepsy cases. PCE is secondary to a recognizable cerebral lesion in 43.5% of the cases; hereditary predisposition to epilepsy exists in about 7% of the cases. The most common causes are: perinatal encephalopathy (anoxic or traumatic), infantile encephalitis, cranio-encephalic trauma, and febrile convulsions lasting more than 30 min. PCE appears before 15 yr of age in 2/3 of the cases; after this age the possibility that PCE will appear decreases progressively. The most common partial complex seizures are those characterized by loss of consciousness only and psychomotor seizures; together they represent more than 3/4 of all partial complex seizures. PCS are associated with other types of seizures in 54.5% of the cases. The most common associated seizures are secondarily generalized partial seizures. PCE patients present permanent neurological deficit in 12.6% of the cases, intelligence deficit in 13.1% (IQ under 80), and personality disorders in 20.3%. Behavior disorders are observed in only 11% of the cases. Only half of the PCE patients present an interictal EEG with specific abnormalities focused on one or both temporal regions. Social insertion of PCE patients is normal in more than half the cases, inferior to the norm in 1/4, and absent in 1/4. Short term evolution of adequately treated PCE appears relatively benign: about 2/3 of the patients improve considerably while only 1/3 remain unchanged. Only 2 factors contribute to a negative prognosis: lesional etiology and the presence of 'sudden drop attacks' or partial elementary seizures in association with the partial complex seizures.

Translated title of the contributionComplex partial epilepsy: Etiologic, clinical and evolutive aspects
Original languageItalian
Pages (from-to)8-30
Number of pages23
JournalRivista di Neurologia
Issue number1
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Clinical Neurology


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