TY - GEN
T1 - Complex search, ranks, and biological discovery
T2 - Workshop on Search Computing - Trends and Developments, SeCo 2010
AU - Romano, Paolo
AU - Milanesi, Luciano
PY - 2011
Y1 - 2011
N2 - This chapter presents a users perspective regarding the potential applications of the Search Computing technology for biomedical discovery. Recent research on human inherited diseases has increased the number of information resources useful to bridge medicine and biology and to associate genotype and phenotype. The application of the Search Computing technology is discussed in the frame of a number of techniques that can be applied in Life Sciences for managing distributed biomedical data: Federated databases, Grids, Cloud computing, Web Services, Workflow. Particular attention is then devoted to challenges and opportunities deriving from the application of ranking and the management of missing information. Finally, the definition of a standard score function, that could be adopted by all service providers in order to merge all the collected scores for the Search Computing, and the combined use of workflow management systems and Search Computing, are discussed.
AB - This chapter presents a users perspective regarding the potential applications of the Search Computing technology for biomedical discovery. Recent research on human inherited diseases has increased the number of information resources useful to bridge medicine and biology and to associate genotype and phenotype. The application of the Search Computing technology is discussed in the frame of a number of techniques that can be applied in Life Sciences for managing distributed biomedical data: Federated databases, Grids, Cloud computing, Web Services, Workflow. Particular attention is then devoted to challenges and opportunities deriving from the application of ranking and the management of missing information. Finally, the definition of a standard score function, that could be adopted by all service providers in order to merge all the collected scores for the Search Computing, and the combined use of workflow management systems and Search Computing, are discussed.
KW - Bioinformatics
KW - Grid computing
KW - Search Computing
KW - web services
KW - workflow
UR - http://www.scopus.com/inward/record.url?scp=79952922353&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79952922353&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-19668-3_21
DO - 10.1007/978-3-642-19668-3_21
M3 - Conference contribution
AN - SCOPUS:79952922353
SN - 9783642196676
VL - 6585 LNCS
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 226
EP - 235
BT - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Y2 - 25 May 2010 through 31 May 2010
ER -