Complex variant Philadelphia translocation involving the short arm of chromosome 9 in a case of chronic myeloid leukemia.

Anna Maria Cianciulli, Raffaella Marzano, Roberta Merola, Giulia Orlandi, M. Concetta Petti, Fiorella Guadagni, Francesco Pisani

Research output: Contribution to journalArticlepeer-review

Abstract

Here we describe how we detected the BCR/ABL fusion gene on the short arm of der(9) combining classical GTG banding and Fluorescence In Situ Hybridization (FISH) in a case of chronic myeloid leukemia (CML). To our knowledge, variant translocations involving the short arm of chromosome 9, in literature, are almost rare in chronic myeloid leukemia. It is not clear if this complex genetic translocation represents clonal evolution or a unique, initial presentation variant of the Philadelphia chromosome (Ph).

Original languageEnglish
JournalHaematologica
Volume89
Issue number9
Publication statusPublished - Sep 2004

ASJC Scopus subject areas

  • Hematology

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