Complicated Acute Type B Dissection: Is Surgery Still the Best Option?. A Report From the International Registry of Acute Aortic Dissection

Rossella Fattori, Thomas T. Tsai, Truls Myrmel, Arturo Evangelista, Jeanna V. Cooper, Santi Trimarchi, Jin Li, Luigi Lovato, Stephan Kische, Kim A. Eagle, Eric M. Isselbacher, Christoph A. Nienaber

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: Impact on survival of different treatment strategies was analyzed in 571 patients with acute type B aortic dissection enrolled from 1996 to 2005 in the International Registry of Acute Aortic Dissection. Background: The optimal treatment for acute type B dissection is still a matter of debate. Methods: Information on 290 clinical variables were compared, including demographics; medical history; clinical presentation; physical findings; imaging studies; details of medical, surgical, and endovascular management; in-hospital clinical events; and in-hospital mortality. Results: Of the 571 patients with acute type B aortic dissection, 390 (68.3%) were treated medically, 59 (10.3%) with standard open surgery and 66 (11.6%) with an endovascular approach. Patients who underwent emergency endovascular or open surgery were younger (mean age 58.8 years, p <0.001) than their counterparts treated conservatively, and had male preponderance and hypertension in 76.9%. Patients submitted to surgery presented with a wider aortic diameter than patients treated by interventional techniques or by medical therapy (5.36 ± 1.7 cm vs. 4.62 ± 1.4 cm vs. 4.47 ± 1.4 cm, p = 0.003). In-hospital complications occurred in 20% of patients subjected to endovascular technique and in 40% of patients after open surgical repair. In-hospital mortality was significantly higher after open surgery (33.9%) than after endovascular treatment (10.6%, p = 0.002). After propensity and multivariable adjustment, open surgical repair was associated with an independent increased risk of in-hospital mortality (odds ratio: 3.41, 95% confidence interval: 1.00 to 11.67, p = 0.05). Conclusions: In the International Registry of Acute Aortic Dissection, the less invasive nature of endovascular treatment seems to provide better in-hospital survival in patients with acute type B dissection; larger randomized trials or comprehensive registries are needed to access impact on outcomes.

Original languageEnglish
Pages (from-to)395-402
Number of pages8
JournalJACC: Cardiovascular Interventions
Volume1
Issue number4
DOIs
Publication statusPublished - Aug 2008

Keywords

  • aorta
  • stent-graft
  • surgery
  • survival

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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