Computational study of aortic hemodynamics: From simplified to patient-specific geometries

A. Lefieux, F. Auricchio, M. Conti, S. Morganti, A. Reali, S. Trimarchi, A. Veneziani

Research output: Contribution to journalArticlepeer-review


The investigation of aortic hemodynamics in physiological and pathological conditions by computational fluid dynamics is still one of the major topic of vascular biomechanics. In particular,thanks to the developments of new endovascular technologies such as Thoracic EndoVAscular Repair (TEVAR),a lot of attention is paid to the hemodynamics analysis of thoracic aorta. In this work,we aim at performing a sensitivity analysis of morphological aspects by comparing numerical results about three cases: (i) an idealized aortic arch with a candy cane shape; (ii) a patient-specific healthy arch; and (iii) a patient-specific dissected aorta. For the idealized aortic arch case we also compare the obtained results with respect to the theoretical and experimental literature dedicated to curved pipes.

Original languageEnglish
Pages (from-to)397-407
Number of pages11
JournalModeling and Simulation in Science, Engineering and Technology
Publication statusPublished - 2016

ASJC Scopus subject areas

  • Fluid Flow and Transfer Processes
  • Engineering(all)
  • Computational Mathematics
  • Modelling and Simulation


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