Computational study of the fluid-dynamics in carotids before and after endarterectomy

Bruno Guerciotti, Christian Vergara, Laura Azzimonti, Laura Forzenigo, Adelaide Buora, Piero Biondetti, Maurizio Domanin

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In this work, we provide a computational study of the effects of carotid endarterectomy (CEA) on the fluid-dynamics at internal carotid bifurcations. We perform numerical simulations in real geometries of the same patients before and after CEA, using patient-specific boundary data obtained by Echo-Color Doppler measurements. We analyze four patients with a primary closure and other four where a patch was used to close arteriotomies. The results show that (i) CEA is able to restore physiological fluid-dynamic conditions; (ii) among the post-operative cases, the presence of patch leads to local hemodynamic conditions which might imply a higher risk of restenosis in comparison with the cases without patch.

Original languageEnglish
Pages (from-to)26-38
Number of pages13
JournalJournal of Biomechanics
Volume49
Issue number1
DOIs
Publication statusPublished - Jan 4 2016

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Endarterectomy
Carotid Endarterectomy
Fluid dynamics
Bifurcation (mathematics)
Hemodynamics
Color
Geometry
Computer simulation

Keywords

  • Carotids
  • CFD
  • Endarterectomy
  • Restenosis

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Rehabilitation
  • Biophysics
  • Biomedical Engineering

Cite this

Computational study of the fluid-dynamics in carotids before and after endarterectomy. / Guerciotti, Bruno; Vergara, Christian; Azzimonti, Laura; Forzenigo, Laura; Buora, Adelaide; Biondetti, Piero; Domanin, Maurizio.

In: Journal of Biomechanics, Vol. 49, No. 1, 04.01.2016, p. 26-38.

Research output: Contribution to journalArticle

Guerciotti, Bruno ; Vergara, Christian ; Azzimonti, Laura ; Forzenigo, Laura ; Buora, Adelaide ; Biondetti, Piero ; Domanin, Maurizio. / Computational study of the fluid-dynamics in carotids before and after endarterectomy. In: Journal of Biomechanics. 2016 ; Vol. 49, No. 1. pp. 26-38.
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