Computed tomography in the detection of the vascular component in dementia

Giovanni B. Frisoni; Alberto Beltramello; Giuliano Binetti; Angelo Bianchetti; Claudia Weiss; Alberto Seuratti; Marco Trabucchi

doi:10.1159/000213672

Computed tomography in the detection of the vascular component in dementia

Giovanni B. Frisoni, Alberto Beltramello, Giuliano Binetti, Angelo Bianchetti, Claudia Weiss, Alberto Seuratti, Marco Trabucchi

Centro San Giovanni di Dio - Fatebenefratelli

Research output: Contribution to journal › Article › peer-review

Abstract

We evaluated the presence and type of vascular lesions with computerized tomography (CT) in 94 cognitively impaired elderly patients who had been defined as degenerative (Alz-heimer’s disease, AD) or vascular (multi-infarct dementia, MID) dementia patients on the basis of clinical data. Twenty- six percent of the 77 AD, but only 59% of the 17 MID patients had vascular lesions. The most represented vascular lesions were leukoaraiosis in AD and hemispherical cortical lesions in MID patients. Age, signs indicative of, and risk factors for vascular disease were associated with vascular lesions on CT. We conclude that CT scan is a necessary complement to historical and clinical data in the detection of vascularity in demented patients.

Original language	English
Pages (from-to)	121-128
Number of pages	8
Journal	Gerontology
Volume	41
Issue number	2
DOIs	https://doi.org/10.1159/000213672
Publication status	Published - 1995

Keywords

Alzheimer’s disease
Cerebrovascular disease
Computerized tomography
Leukoaraiosis
Mixed dementia
Multi-infarct dementia
Vascular dementia

ASJC Scopus subject areas

Ageing
Geriatrics and Gerontology

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title = "Computed tomography in the detection of the vascular component in dementia",

abstract = "We evaluated the presence and type of vascular lesions with computerized tomography (CT) in 94 cognitively impaired elderly patients who had been defined as degenerative (Alz-heimer{\textquoteright}s disease, AD) or vascular (multi-infarct dementia, MID) dementia patients on the basis of clinical data. Twenty- six percent of the 77 AD, but only 59% of the 17 MID patients had vascular lesions. The most represented vascular lesions were leukoaraiosis in AD and hemispherical cortical lesions in MID patients. Age, signs indicative of, and risk factors for vascular disease were associated with vascular lesions on CT. We conclude that CT scan is a necessary complement to historical and clinical data in the detection of vascularity in demented patients.",

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AU - Frisoni, Giovanni B.

AU - Beltramello, Alberto

AU - Binetti, Giuliano

AU - Bianchetti, Angelo

AU - Weiss, Claudia

AU - Seuratti, Alberto

AU - Trabucchi, Marco

PY - 1995

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N2 - We evaluated the presence and type of vascular lesions with computerized tomography (CT) in 94 cognitively impaired elderly patients who had been defined as degenerative (Alz-heimer’s disease, AD) or vascular (multi-infarct dementia, MID) dementia patients on the basis of clinical data. Twenty- six percent of the 77 AD, but only 59% of the 17 MID patients had vascular lesions. The most represented vascular lesions were leukoaraiosis in AD and hemispherical cortical lesions in MID patients. Age, signs indicative of, and risk factors for vascular disease were associated with vascular lesions on CT. We conclude that CT scan is a necessary complement to historical and clinical data in the detection of vascularity in demented patients.

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