Computerized cranial tomography in Wilson disease: Report of a case before and after penicillamine therapy

G. Lanci, U. Balottin, A. Cecchini, A. Ottolini

Research output: Contribution to journalArticle

Abstract

A patient with Wilson's Disease presenting neurologic signs was treated with d-Penicillamine. Computerized cranial tomography (CT) performed before therapy showed symmetrical areas of low density in the region of the basal ganglia, enlargement of ventricles, and bilateral increased density of the medial nuclei of the thalamus. This abnormality of the thalamus had not been reported previously in Wilson's disease. After two years' therapy there was an evident clinical improvement and at the same time a reduction of the CT abnormalities. The reports on CT scanning in Wilson's disease are reviewed.

Original languageEnglish
Pages (from-to)383-386
Number of pages4
JournalItalian Journal of Neurological Sciences
Volume2
Issue number4
Publication statusPublished - 1981

Fingerprint

Hepatolenticular Degeneration
Penicillamine
Tomography
Thalamus
Neurologic Manifestations
Basal Ganglia
Therapeutics

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Computerized cranial tomography in Wilson disease : Report of a case before and after penicillamine therapy. / Lanci, G.; Balottin, U.; Cecchini, A.; Ottolini, A.

In: Italian Journal of Neurological Sciences, Vol. 2, No. 4, 1981, p. 383-386.

Research output: Contribution to journalArticle

@article{aeb7a653299d4f6c817545b8f9ae252c,
title = "Computerized cranial tomography in Wilson disease: Report of a case before and after penicillamine therapy",
abstract = "A patient with Wilson's Disease presenting neurologic signs was treated with d-Penicillamine. Computerized cranial tomography (CT) performed before therapy showed symmetrical areas of low density in the region of the basal ganglia, enlargement of ventricles, and bilateral increased density of the medial nuclei of the thalamus. This abnormality of the thalamus had not been reported previously in Wilson's disease. After two years' therapy there was an evident clinical improvement and at the same time a reduction of the CT abnormalities. The reports on CT scanning in Wilson's disease are reviewed.",
author = "G. Lanci and U. Balottin and A. Cecchini and A. Ottolini",
year = "1981",
language = "English",
volume = "2",
pages = "383--386",
journal = "Italian Journal of Neurological Sciences",
issn = "0392-0461",
publisher = "Springer Verlag",
number = "4",

}

TY - JOUR

T1 - Computerized cranial tomography in Wilson disease

T2 - Report of a case before and after penicillamine therapy

AU - Lanci, G.

AU - Balottin, U.

AU - Cecchini, A.

AU - Ottolini, A.

PY - 1981

Y1 - 1981

N2 - A patient with Wilson's Disease presenting neurologic signs was treated with d-Penicillamine. Computerized cranial tomography (CT) performed before therapy showed symmetrical areas of low density in the region of the basal ganglia, enlargement of ventricles, and bilateral increased density of the medial nuclei of the thalamus. This abnormality of the thalamus had not been reported previously in Wilson's disease. After two years' therapy there was an evident clinical improvement and at the same time a reduction of the CT abnormalities. The reports on CT scanning in Wilson's disease are reviewed.

AB - A patient with Wilson's Disease presenting neurologic signs was treated with d-Penicillamine. Computerized cranial tomography (CT) performed before therapy showed symmetrical areas of low density in the region of the basal ganglia, enlargement of ventricles, and bilateral increased density of the medial nuclei of the thalamus. This abnormality of the thalamus had not been reported previously in Wilson's disease. After two years' therapy there was an evident clinical improvement and at the same time a reduction of the CT abnormalities. The reports on CT scanning in Wilson's disease are reviewed.

UR - http://www.scopus.com/inward/record.url?scp=0019804546&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019804546&partnerID=8YFLogxK

M3 - Article

C2 - 7333829

AN - SCOPUS:0019804546

VL - 2

SP - 383

EP - 386

JO - Italian Journal of Neurological Sciences

JF - Italian Journal of Neurological Sciences

SN - 0392-0461

IS - 4

ER -