Computerized mapping system of cerebral evoked potentials

Fabio Babiloni, Sonia Cracas, Paul B. Johnson, Serenella Salinari, Antonio Urbano

Research output: Contribution to journalArticlepeer-review


The introduction of computerized analysis systems in the study of bioelectrical signals is enhancing the understanding of the physiological mechanisms which underlie cerebral evoked potentials (EPs) in response to externally applied stimuli. In the present study, short latency (0-50-ms) and long latency (0-500-ms) somatosensory evoked potentials (SEPs) were recorded by 32 scalp electrodes from normal and pathological subjects during median nerve stimulation. An interpolation procedure for estimating data values between the neigh-boring electrodes allowed the mapping of cortical activity across the scalp. Time signals were also transformed by an FFT algorithm and frequency maps obtained following the same interpolation procedure. Temporal and frequency maps were graphically displayed using color and three-dimensional plots. The usefulness of computerized topographical analysis is discussed; the time and frequency computer maps obtained from the same subjects are compared and their relative advantages are evaluated.

Original languageEnglish
Pages (from-to)165-178
Number of pages14
JournalComputers and Biomedical Research
Issue number2
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Medicine (miscellaneous)


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