STABILOMETRIA COMPUTERIZZATA IN PAZIENTI CON EPILESSIA IN MONOTERAPIA CON FENITOINA E CARBAMAZEPINA

C. A. Tassinari; F. Valzania; P. Riguzzi; M. Santangelo; G. Ambrosetto

STABILOMETRIA COMPUTERIZZATA IN PAZIENTI CON EPILESSIA IN MONOTERAPIA CON FENITOINA E CARBAMAZEPINA

Translated title of the contribution: Computerized stabilometry in patients with epilepsy treated with phenytoin or carbamazepine

C. A. Tassinari, F. Valzania, P. Riguzzi, M. Santangelo, G. Ambrosetto

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article › peer-review

Abstract

Computerized stabilometry was performed in 17 epileptic patients treated with phenytoin (PHT) and in 35 epileptic patients treated with carbamazepine (CBZ). Postural instability was observed in 10/10 patients with PHT plasma levels (P.L.) over 17 mcg/ml and in 1/7 patient with P.L. under 17 mcg/ml (p <0.001). Concerning CBZ-treated patients, 10/16 with P.L. over 7.5 mcg/ml and 5/19 with P.L. lower than 7.5 mcg/ml showed abnormal stability. This study suggests that postural instability is observed: 1) in PHT treated patients when P.L. are over a critical value (17 mcg/ml); 2) in CBZ treated patients, when P.L. are over an individual threshold, varying from subject to subject.

Translated title of the contribution	Computerized stabilometry in patients with epilepsy treated with phenytoin or carbamazepine
Original language	Italian
Pages (from-to)	77-78
Number of pages	2
Journal	Bollettino - Lega Italiana contro l'Epilessia
Issue number	74
Publication status	Published - 1991

ASJC Scopus subject areas

Clinical Neurology

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Cite this

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title = "STABILOMETRIA COMPUTERIZZATA IN PAZIENTI CON EPILESSIA IN MONOTERAPIA CON FENITOINA E CARBAMAZEPINA",

abstract = "Computerized stabilometry was performed in 17 epileptic patients treated with phenytoin (PHT) and in 35 epileptic patients treated with carbamazepine (CBZ). Postural instability was observed in 10/10 patients with PHT plasma levels (P.L.) over 17 mcg/ml and in 1/7 patient with P.L. under 17 mcg/ml (p <0.001). Concerning CBZ-treated patients, 10/16 with P.L. over 7.5 mcg/ml and 5/19 with P.L. lower than 7.5 mcg/ml showed abnormal stability. This study suggests that postural instability is observed: 1) in PHT treated patients when P.L. are over a critical value (17 mcg/ml); 2) in CBZ treated patients, when P.L. are over an individual threshold, varying from subject to subject.",

author = "Tassinari, {C. A.} and F. Valzania and P. Riguzzi and M. Santangelo and G. Ambrosetto",

year = "1991",

language = "Italian",

pages = "77--78",

journal = "Bollettino - Lega Italiana contro l'Epilessia",

issn = "0394-560X",

publisher = "Lega Italiana contro l'Epilessia",

number = "74",

}

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T1 - STABILOMETRIA COMPUTERIZZATA IN PAZIENTI CON EPILESSIA IN MONOTERAPIA CON FENITOINA E CARBAMAZEPINA

AU - Tassinari, C. A.

AU - Valzania, F.

AU - Riguzzi, P.

AU - Santangelo, M.

AU - Ambrosetto, G.

PY - 1991

Y1 - 1991

N2 - Computerized stabilometry was performed in 17 epileptic patients treated with phenytoin (PHT) and in 35 epileptic patients treated with carbamazepine (CBZ). Postural instability was observed in 10/10 patients with PHT plasma levels (P.L.) over 17 mcg/ml and in 1/7 patient with P.L. under 17 mcg/ml (p <0.001). Concerning CBZ-treated patients, 10/16 with P.L. over 7.5 mcg/ml and 5/19 with P.L. lower than 7.5 mcg/ml showed abnormal stability. This study suggests that postural instability is observed: 1) in PHT treated patients when P.L. are over a critical value (17 mcg/ml); 2) in CBZ treated patients, when P.L. are over an individual threshold, varying from subject to subject.

AB - Computerized stabilometry was performed in 17 epileptic patients treated with phenytoin (PHT) and in 35 epileptic patients treated with carbamazepine (CBZ). Postural instability was observed in 10/10 patients with PHT plasma levels (P.L.) over 17 mcg/ml and in 1/7 patient with P.L. under 17 mcg/ml (p <0.001). Concerning CBZ-treated patients, 10/16 with P.L. over 7.5 mcg/ml and 5/19 with P.L. lower than 7.5 mcg/ml showed abnormal stability. This study suggests that postural instability is observed: 1) in PHT treated patients when P.L. are over a critical value (17 mcg/ml); 2) in CBZ treated patients, when P.L. are over an individual threshold, varying from subject to subject.

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JO - Bollettino - Lega Italiana contro l'Epilessia

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