Computing DIT from energy expenditure measures in a respiratory chamber: A direct modeling method

S. Marino, A. De Gaetano, A. Giancaterini, D. Giordano, M. Manco, A. V. Greco, G. Mingrone

Research output: Contribution to journalArticlepeer-review

Abstract

The possibility of computing Diet Induced Thermogenesis (DIT) is an important feature of metabolic investigations. However, methodological problems have affected the determination of DIT in the indirect calorimetric chamber. DIT has been commonly estimated by regressing energy expenditure on a measure of physical activity. Although used for many years as the only feasible approach to calculate DIT in a respiratory chamber, this traditional method has been criticized because of an apparent underestimation of the DIT, but no alternative method has been suggested so far. The present work proposes to estimate DIT directly by means of a mathematical model. This approach also allows to simultaneously estimate other parameters, namely resting energy expenditure (REE), physical activity (PA) and physical exercise (PE).

Original languageEnglish
Pages (from-to)297-309
Number of pages13
JournalComputers in Biology and Medicine
Volume32
Issue number4
DOIs
Publication statusPublished - 2002

Keywords

  • Diet Induced Thermogenesis
  • Energy Expenditure
  • Mathematical Model
  • Obesity

ASJC Scopus subject areas

  • Computer Science Applications

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