Concurrence of localized Castleman's disease and peripheral small B-lymphocytic lymphoma within the same lymph node

G. F. Orcioni, V. Mambelli, S. Ascani, E. Sabattini, M. Piccioli, F. Pieri, B. Falini, S. A. Pileri

Research output: Contribution to journalArticle

Abstract

Castleman's disease, also known as benign giant lymph node hyperplasia, is a lymphoproliferative disorder which can occur either in a localized or multicentric form. The latter is characterized by the development of malignant lymphoma, Kaposi's sarcoma or carcinoma in 32% of cases. By contrast, localized Castleman's disease has exceptionally been reported in association with non-Hodgkin's lymphoma and - to the best of our knowledge - never at the same anatomic site. Here we describe the occurrence in the same lymph node of localized Castleman's disease (with monotypic plasma cell component) and an apparently unrelated peripheral small B-lymphocytic lymphoma.

Original languageEnglish
Pages (from-to)327-330
Number of pages4
JournalGeneral and Diagnostic Pathology
Volume143
Issue number5-6
Publication statusPublished - 1998

    Fingerprint

Keywords

  • Castleman's disease
  • Immunohistochemistry
  • Malignant lymphoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Orcioni, G. F., Mambelli, V., Ascani, S., Sabattini, E., Piccioli, M., Pieri, F., Falini, B., & Pileri, S. A. (1998). Concurrence of localized Castleman's disease and peripheral small B-lymphocytic lymphoma within the same lymph node. General and Diagnostic Pathology, 143(5-6), 327-330.