Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands

A. Fiorentino, M. Cozzolino, R. Caivano, P. Pedicini, C. Chiumento, C. Oliviero, S. Clemente, V. Fusco

Research output: Contribution to journalArticle

Abstract

Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). ThePGmean dose (D mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCT plan I. The Dmean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.

Original languageEnglish
Pages (from-to)412-415
Number of pages4
JournalClinical and Translational Oncology
Volume15
Issue number5
DOIs
Publication statusPublished - May 2013

Keywords

  • Head and neck cancer
  • IMRT
  • Organ at risk
  • Parotid glands
  • Radiotherapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Medicine(all)

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