Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands

A. Fiorentino; M. Cozzolino; R. Caivano; P. Pedicini; C. Chiumento; C. Oliviero; S. Clemente; V. Fusco

doi:10.1007/s12094-012-0946-4

Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands

A. Fiorentino, M. Cozzolino, R. Caivano, P. Pedicini, C. Chiumento, C. Oliviero, S. Clemente, V. Fusco

IRCCS Centro di Riferimento Oncologico della Basilicata (CROB)

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CT_plan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCT_plan I and II, respectively). ThePGmean dose (D _mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CT_plan was compared to CBCT _plan I. The D_mean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.

Original language	English
Pages (from-to)	412-415
Number of pages	4
Journal	Clinical and Translational Oncology
Volume	15
Issue number	5
DOIs	https://doi.org/10.1007/s12094-012-0946-4
Publication status	Published - May 2013

Keywords

Head and neck cancer
IMRT
Organ at risk
Parotid glands
Radiotherapy

ASJC Scopus subject areas

Oncology
Cancer Research
Medicine(all)

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10.1007/s12094-012-0946-4

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Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer : Parotid glands. / Fiorentino, A.; Cozzolino, M.; Caivano, R.; Pedicini, P.; Chiumento, C.; Oliviero, C.; Clemente, S.; Fusco, V.

In: Clinical and Translational Oncology, Vol. 15, No. 5, 05.2013, p. 412-415.

Research output: Contribution to journal › Article › peer-review

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abstract = "Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). ThePGmean dose (D mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCT plan I. The Dmean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.",

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doi = "10.1007/s12094-012-0946-4",

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T2 - Parotid glands

AU - Fiorentino, A.

AU - Cozzolino, M.

AU - Caivano, R.

AU - Pedicini, P.

AU - Chiumento, C.

AU - Oliviero, C.

AU - Clemente, S.

AU - Fusco, V.

PY - 2013/5

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N2 - Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). ThePGmean dose (D mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCT plan I. The Dmean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.

AB - Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). ThePGmean dose (D mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCT plan I. The Dmean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.

KW - Head and neck cancer

KW - IMRT

KW - Organ at risk

KW - Parotid glands

KW - Radiotherapy

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Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands

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