Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands

A. Fiorentino; M. Cozzolino; R. Caivano; P. Pedicini; C. Chiumento; C. Oliviero; S. Clemente; V. Fusco

doi:10.1007/s12094-012-0946-4

Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands

A. Fiorentino, M. Cozzolino, R. Caivano, P. Pedicini, C. Chiumento, C. Oliviero, S. Clemente, V. Fusco

IRCCS Centro di Riferimento Oncologico della Basilicata (CROB)

Research output: Contribution to journal › Article

Abstract

Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CT_plan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCT_plan I and II, respectively). ThePGmean dose (D _mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CT_plan was compared to CBCT _plan I. The D_mean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.

Original language	English
Pages (from-to)	412-415
Number of pages	4
Journal	Clinical and Translational Oncology
Volume	15
Issue number	5
DOIs	https://doi.org/10.1007/s12094-012-0946-4
Publication status	Published - May 2013

Keywords

Head and neck cancer
IMRT
Organ at risk
Parotid glands
Radiotherapy

ASJC Scopus subject areas

Oncology
Cancer Research
Medicine(all)

Access to Document

10.1007/s12094-012-0946-4

Fingerprint Dive into the research topics of 'Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands'. Together they form a unique fingerprint.

Cite this

Fiorentino, A., Cozzolino, M., Caivano, R., Pedicini, P., Chiumento, C., Oliviero, C., Clemente, S., & Fusco, V. (2013). Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands. Clinical and Translational Oncology, 15(5), 412-415. https://doi.org/10.1007/s12094-012-0946-4

Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer : Parotid glands. / Fiorentino, A.; Cozzolino, M.; Caivano, R.; Pedicini, P.; Chiumento, C.; Oliviero, C.; Clemente, S.; Fusco, V.

In: Clinical and Translational Oncology, Vol. 15, No. 5, 05.2013, p. 412-415.

Research output: Contribution to journal › Article

@article{9de683f525d3491ca4086f3b88a0b988,

title = "Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer: Parotid glands",

abstract = "Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). ThePGmean dose (D mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCT plan I. The Dmean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.",

keywords = "Head and neck cancer, IMRT, Organ at risk, Parotid glands, Radiotherapy",

author = "A. Fiorentino and M. Cozzolino and R. Caivano and P. Pedicini and C. Chiumento and C. Oliviero and S. Clemente and V. Fusco",

year = "2013",

month = may,

doi = "10.1007/s12094-012-0946-4",

language = "English",

volume = "15",

pages = "412--415",

journal = "Clinical and Translational Oncology",

issn = "1699-048X",

publisher = "Springer-Verlag Italia",

number = "5",

}

TY - JOUR

T1 - Cone-beam computed tomography dose monitoring during intensity-modulated radiotherapy in head and neck cancer

T2 - Parotid glands

AU - Fiorentino, A.

AU - Cozzolino, M.

AU - Caivano, R.

AU - Pedicini, P.

AU - Chiumento, C.

AU - Oliviero, C.

AU - Clemente, S.

AU - Fusco, V.

PY - 2013/5

Y1 - 2013/5

N2 - Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). ThePGmean dose (D mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCT plan I. The Dmean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.

AB - Purpose To evaluate the dosimetric changes of parotid glands (PG) during a course of intensity-modulated radiotherapy (IMRT) in head and neck (H&N) cancer patients. Methods Ten patients with H&N cancer treated by IMRT were analyzed. The original treatment plan (CTplan) was transferred to cone-beam computed tomography (CBCT) acquired at the 15th and 20th treatment day (CBCTplan I and II, respectively). ThePGmean dose (D mean), the dose to 50 % of the volume, and the percent of volume receiving 30 and 50 Gy were measured by the dose volume histogram. Results 30 IMRT plans were evaluated (3 plans/patient). All dosimetric end points increased significantly for both PG only when CTplan was compared to CBCT plan I. The Dmean increased significantly only for ipsilateral PG (p = 0.02) at week 3. Conclusion During a course of IMRT, CBCT is a feasible method to check the PG dosimetric variations. Perhaps, the 3rd week of radiotherapy could be considered as the timecheck- point.

KW - Head and neck cancer

KW - IMRT

KW - Organ at risk

KW - Parotid glands

KW - Radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=84887392843&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84887392843&partnerID=8YFLogxK

U2 - 10.1007/s12094-012-0946-4

DO - 10.1007/s12094-012-0946-4

M3 - Article

C2 - 23065602

AN - SCOPUS:84887392843

VL - 15

SP - 412

EP - 415

JO - Clinical and Translational Oncology

JF - Clinical and Translational Oncology

SN - 1699-048X

IS - 5

ER -