TY - JOUR
T1 - Confocal features of equivocal facial lesions on severely sun-damaged skin
T2 - Four case studies with dermatoscopic, confocal, and histopathologic correlation
AU - Wurm, Elisabeth M T
AU - Curchin, Claudia E S
AU - Lambie, Duncan
AU - Longo, Caterina
AU - Pellacani, Giovanni
AU - Soyer, H. Peter
PY - 2012/3
Y1 - 2012/3
N2 - Background: Facial skin has a distinct histologic architecture and reveals specific dermatoscopic features. Diagnosis of lentigo maligna on the face is often challenging because of the overlap of clinical and morphologic features with other lesions. Objectives: We aim to show the value of reflectance confocal microscopy (RCM) as a noninvasive diagnostic tool for facial lesions and to increase knowledge of RCM morphologic features among the scientific community. Methods: We describe a series of 4 facial lesions on severely sun-damaged skin that was evaluated via RCM immediately after face-to-face examination, followed by shave biopsy for histopathological analysis. Results: Lesions included a lentigo maligna, a pigmented seborrheic keratosis, pigmented basal cell carcinoma, and a pigmented actinic keratosis. In the presented cases, RCM enabled an accurate diagnosis. Limitations: The study describes morphologic features on selected cases, but does not test accuracy of RCM criteria. Conclusions: RCM is a useful adjuvant for the accurate and precise diagnosis of equivocal facial lesions.
AB - Background: Facial skin has a distinct histologic architecture and reveals specific dermatoscopic features. Diagnosis of lentigo maligna on the face is often challenging because of the overlap of clinical and morphologic features with other lesions. Objectives: We aim to show the value of reflectance confocal microscopy (RCM) as a noninvasive diagnostic tool for facial lesions and to increase knowledge of RCM morphologic features among the scientific community. Methods: We describe a series of 4 facial lesions on severely sun-damaged skin that was evaluated via RCM immediately after face-to-face examination, followed by shave biopsy for histopathological analysis. Results: Lesions included a lentigo maligna, a pigmented seborrheic keratosis, pigmented basal cell carcinoma, and a pigmented actinic keratosis. In the presented cases, RCM enabled an accurate diagnosis. Limitations: The study describes morphologic features on selected cases, but does not test accuracy of RCM criteria. Conclusions: RCM is a useful adjuvant for the accurate and precise diagnosis of equivocal facial lesions.
KW - basal cell carcinoma
KW - dermatoscopy
KW - face
KW - histopathology
KW - lentigo maligna
KW - photodamaged skin
KW - pigmented actinic keratosis
KW - reflectance confocal microscopy
KW - seborrheic keratosis
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U2 - 10.1016/j.jaad.2011.02.040
DO - 10.1016/j.jaad.2011.02.040
M3 - Article
C2 - 21978574
AN - SCOPUS:84857448338
VL - 66
SP - 463
EP - 473
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
SN - 0190-9622
IS - 3
ER -