Confocal microscopy: Improving our understanding of nevogenesis

Barbara De Pace, Barbara Ferrari, Barbara Predieri, Lorenzo Iughetti, Leonardo Veneziano, Iris Zalaudek, Giuseppe Argenziano, Caterina Longo, Giovanni Pellacani

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Nevi are benign clonal proliferations of cells expressing a melanocytic phenotype. The development of melanocytic nevi is a complex, multifactorial process. In some conditions, it has been demonstrated that genetic factors (i.e., numerical and structural abnormalities of chromosomes, mutant genes, genetic mosaic) or environmental factors (i.e., intrauterine infections, ionizing radiation, drugs, alcohol, deficiency or excess of trace elements in pregnancy, maternal diseases) or combinations of both may play a role. However, in almost all cases the etiology remains unknown.

Original languageEnglish
Title of host publicationNevogenesis: Mechanisms and Clinical Implications of Nevus Development
PublisherSpringer Berlin Heidelberg
Pages59-67
Number of pages9
ISBN (Print)9783642283970, 9783642283963
DOIs
Publication statusPublished - Jan 1 2012

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Confocal microscopy: Improving our understanding of nevogenesis'. Together they form a unique fingerprint.

  • Cite this

    De Pace, B., Ferrari, B., Predieri, B., Iughetti, L., Veneziano, L., Zalaudek, I., Argenziano, G., Longo, C., & Pellacani, G. (2012). Confocal microscopy: Improving our understanding of nevogenesis. In Nevogenesis: Mechanisms and Clinical Implications of Nevus Development (pp. 59-67). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-28397-0_5