Confocal scanning laser ophthalmoscope in the retromode imaging modality in exudative age-related macular degeneration

Elisabetta Pilotto, Patrik Sportiello, Ernesto Alemany-Rubio, Stela Vujosevic, Sara Segalina, Iva Fregona, Edoardo Midena

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To evaluate the ability of confocal scanning laser ophthalmoscope (cSLO) in the retromode imaging modality in detecting retinal changes secondary to exudative age-related macular degeneration (AMD). Methods: Seventeen eyes of 13 consecutive patients affected by CNV secondary to AMD were evaluated with optical coherence tomography (OCT) to detect neuroretinal detachment (NRD), pigment epithelial detachment (PED), cystoid macular edema (CME), and epiretinal membranes (ERM). All eyes were examined with a cSLO equipped with infrared retromode (RM) imaging modality. Infrared and fundus autofluorescence images were also obtained (IR and FAF). The intermethod agreement between OCT and cSLO was evaluated considering single cSLO imaging modality separately (IR, FAF, and RM), and all imaging modalities together. Results: Eight eyes (47 %) had NRD at OCT; intermethod agreement was poor for any single cSLO imaging modality considered separately (k: 0.14, 0.01, and 0.29 for cSLO IR, FAF, and RM, respectively). Four eyes had PED at OCT (24 %); intermethod agreement was mild for cSLO RM, poor for IR and FAF (k: 0.51, 0.16, and 0.00, respectively). CME was present in eight eyes (47 %); intermethod agreement was excellent for cSLO RM, poor for IR and FAF (k: 0.88, 0.38, and 0.26, respectively). ERM was present in three eyes (18 %); intermethod agreement was mild for cSLO IR, poor for FAF, and excellent for RM (k: 0.59, 0.00, and 0.76, respectively). Conclusions: cSLO RM imaging is a useful and reproducible technique in detecting retinal features associated with CNV, particularly CME.

Original languageEnglish
Pages (from-to)27-34
Number of pages8
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume251
Issue number1
DOIs
Publication statusPublished - Jan 2013

Keywords

  • Confocal scanning laser ophthalmoscope
  • Exudative age-related macular degeneration
  • Fundus autofluorescence
  • Optical coherence tomography
  • Retromode retinal imaging

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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