Becker's nevus is a relatively common organic hamartoma, with a rare familial or congenital presentation. Although benign in nature, it may be the cutaneous marker for underlying structural anomalies, especially in female patients. A woman affected by a congenital Becker's nevus involving the anterior chest associated with ipsilateral breast hypoplasia is reported. A review of the international literature shows six other patients with Becker's nevus and breast hypoplasia. This occurrence does not seem accidental, and may be explained by a high local sensibility to androgens, since an abnormal concentration of androgen receptors has been demonstrated in Becker's nevi. The concept of paradominant inheritance has been introduced in order to justify the increased risk for developing Becker's nevus in relatives of affected patients.
|Translated title of the contribution||Congenital Becker's nevus with ipsilateral breast hypoplasia|
|Number of pages||4|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1994|
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