Infezione congenita da citomegalovirus. Parte 1

Cytomegalovirus congenital infection (CMV) is the most common cause of congenital infection worldwide, with a prevalence of 0,6-0,7% of all live-bom infants in the developed countries, this estimated is more precise than 0,2-2,5% often cited in literature. Eighty-five to 90% of the infected newborns are asymptomatic at birth, while 5-15% are symptomatic. Both symptomatic and asymptomatic newborns, have risk of undergoing sequelae. About 20-30% of all infected neonates will exhibit abnormalities, thus congenital CMV is the leading cause of non genetic SHNL and mental retardation in infants. This paper would provide information to guide diagnosis, therapy, clinical care and follow-up of infected newborns.