TY - JOUR
T1 - Congenital diaphragmatic hernia associated with ipsilateral upper limb reduction defects
T2 - Report of a case with thumb hypoplasia
AU - Lerone, M.
AU - Soliani, M.
AU - Corea, D.
AU - Romeo, G.
AU - Martucciello, G.
AU - Silengo, M. C.
PY - 1992
Y1 - 1992
N2 - Four unrelated cases of congenital diaphragmatic hernia associated with ipsilateral upper limb reduction defects were reported by McCredie and Reid in 1978 (J Pediatr 92: 762-765). As contiguous segments of the cervical neural crest are involved in the development of diaphragm and arms, the authors suggested that an early injury to the cervical neural crest might be the common underlying pathogenesis. We describe here a further example of this malformation complex: a newborn with a left posterolateral diaphragmatic hernia associated with ipsilateral thumb hypoplasia.
AB - Four unrelated cases of congenital diaphragmatic hernia associated with ipsilateral upper limb reduction defects were reported by McCredie and Reid in 1978 (J Pediatr 92: 762-765). As contiguous segments of the cervical neural crest are involved in the development of diaphragm and arms, the authors suggested that an early injury to the cervical neural crest might be the common underlying pathogenesis. We describe here a further example of this malformation complex: a newborn with a left posterolateral diaphragmatic hernia associated with ipsilateral thumb hypoplasia.
KW - Bochdalek diaphragmatic hernia
KW - cervical neural crest
KW - malformation complex
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U2 - 10.1002/ajmg.1320440623
DO - 10.1002/ajmg.1320440623
M3 - Article
C2 - 1481856
AN - SCOPUS:0027051408
VL - 44
SP - 827
EP - 829
JO - American Journal of Medical Genetics, Part A
JF - American Journal of Medical Genetics, Part A
SN - 1552-4825
IS - 6
ER -