Congenital glioblastoma

G. M. Milano, C. Cerri, V. Ferruzzi, I. Capolsini, E. Mastrodicasa, L. Genitori, F. Aversa

Research output: Contribution to journalArticle

Abstract

We describe the case a 2-day-old female with congenital glioblastoma. Total resection was followed by adjuvant and high dose chemotherapy, as indicated by the current Italian infant protocol. The child is alive and well 18 months after diagnosis. A review of 67 selected congenital brain tumors showed the mortality rate was 82%. Even though the majority of patients had glioblastoma, only 5/67 had received adjuvant therapy. To ensure optimal outcomes, we recommend total or subtotal surgical resection, followed by adjuvant and high dose chemotherapy. Given the lack specific protocols for congenital brain tumors an international consensus seems to be needed, starting with congenital glioblastoma.

Original languageEnglish
Pages (from-to)124-126
Number of pages3
JournalPediatric Blood and Cancer
Volume53
Issue number1
DOIs
Publication statusPublished - Jul 15 2009

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Keywords

  • Chemotherapy
  • Congenital brain tumors
  • High dose chemotherapy
  • Infant

ASJC Scopus subject areas

  • Medicine(all)
  • Hematology
  • Oncology
  • Pediatrics, Perinatology, and Child Health

Cite this

Milano, G. M., Cerri, C., Ferruzzi, V., Capolsini, I., Mastrodicasa, E., Genitori, L., & Aversa, F. (2009). Congenital glioblastoma. Pediatric Blood and Cancer, 53(1), 124-126. https://doi.org/10.1002/pbc.22008