Congenital glioblastoma

G. M. Milano; C. Cerri; V. Ferruzzi; I. Capolsini; E. Mastrodicasa; L. Genitori; F. Aversa

doi:10.1002/pbc.22008

Congenital glioblastoma

G. M. Milano, C. Cerri, V. Ferruzzi, I. Capolsini, E. Mastrodicasa, L. Genitori, F. Aversa

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the case a 2-day-old female with congenital glioblastoma. Total resection was followed by adjuvant and high dose chemotherapy, as indicated by the current Italian infant protocol. The child is alive and well 18 months after diagnosis. A review of 67 selected congenital brain tumors showed the mortality rate was 82%. Even though the majority of patients had glioblastoma, only 5/67 had received adjuvant therapy. To ensure optimal outcomes, we recommend total or subtotal surgical resection, followed by adjuvant and high dose chemotherapy. Given the lack specific protocols for congenital brain tumors an international consensus seems to be needed, starting with congenital glioblastoma.

Original language	English
Pages (from-to)	124-126
Number of pages	3
Journal	Pediatric Blood and Cancer
Volume	53
Issue number	1
DOIs	https://doi.org/10.1002/pbc.22008
Publication status	Published - Jul 15 2009

Keywords

Chemotherapy
Congenital brain tumors
High dose chemotherapy
Infant

ASJC Scopus subject areas

Medicine(all)
Hematology
Oncology
Pediatrics, Perinatology, and Child Health

Access to Document

10.1002/pbc.22008

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Cite this

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AU - Milano, G. M.

AU - Cerri, C.

AU - Ferruzzi, V.

AU - Capolsini, I.

AU - Mastrodicasa, E.

AU - Genitori, L.

AU - Aversa, F.

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