TY - JOUR
T1 - Congenital heart defects
T2 - 15 Years of experience of the Emilia-Romagna Registry (Italy)
AU - Calzolari, E.
AU - Garani, G.
AU - Cocchi, G.
AU - Magnani, C.
AU - Rivieri, F.
AU - Neville, A.
AU - Astolfi, G.
AU - Baroncini, A.
AU - Garavelli, L.
AU - Gualandi, F.
AU - Scorrano, M.
AU - Bosi, G.
PY - 2003
Y1 - 2003
N2 - Objectives: Collection and assessment of data from the Emilia-Romagna Region on the occurrence of congenital heart defects in order to identify an homogeneous group of patients for further aetiologic and genetic studies. Materials and methods: The present study is based on 1549 stillborn and live born babies affected by congenital heart defect out of 330,017 consecutive births (4.7 per 1000). Results: The frequency and type of congenital heart defects have been identified together with the sex ratio, associated extracardiac anomalies, chromosomal anomalies and the risk of precurrence in relatives. The impact of prenatal diagnosis on prevalence was low during the study period. Conclusions: The study has provided epidemiological data for public health surveillance of congenital heart defects in the Emilia-Romagna region. The creation of a system for the nationwide recording of congenital heart defects designed with regard to the sources of ascertainment, the diagnostic criteria, and the system of classification is emphasised.
AB - Objectives: Collection and assessment of data from the Emilia-Romagna Region on the occurrence of congenital heart defects in order to identify an homogeneous group of patients for further aetiologic and genetic studies. Materials and methods: The present study is based on 1549 stillborn and live born babies affected by congenital heart defect out of 330,017 consecutive births (4.7 per 1000). Results: The frequency and type of congenital heart defects have been identified together with the sex ratio, associated extracardiac anomalies, chromosomal anomalies and the risk of precurrence in relatives. The impact of prenatal diagnosis on prevalence was low during the study period. Conclusions: The study has provided epidemiological data for public health surveillance of congenital heart defects in the Emilia-Romagna region. The creation of a system for the nationwide recording of congenital heart defects designed with regard to the sources of ascertainment, the diagnostic criteria, and the system of classification is emphasised.
KW - Congenital heart defects
KW - Epidemiology
KW - Genetics
KW - Registry
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U2 - 10.1023/A:1025312603880
DO - 10.1023/A:1025312603880
M3 - Article
C2 - 12974553
AN - SCOPUS:0041425094
VL - 18
SP - 773
EP - 780
JO - European Journal of Epidemiology
JF - European Journal of Epidemiology
SN - 0393-2990
IS - 8
ER -