Congenital intestinal anomalies, neonatal short bowel syndrome, and prenatal/neonatal counseling

Germana Casaccia, Alessandro Trucchi, Ioannis Spirydakis, Claudio Giorlandino, Lucia Aite, Irma Capolupo, Onofrio Antonio Catalano, Pietro Bagolan

Research output: Contribution to journalArticle

Abstract

Background: Short bowel syndrome (SBS) is a severe malabsorption caused by bowel loss. Congenital intestinal anomalies (CIA) detectable by prenatal ultrasound as jejunoileal atresia, meconium peritonitis, complicated meconium ileus, and fetal volvulus can be responsible for SBS. Aims: This study aims to investigate either frequency of SBS or the morbidity in CIA population during the first admission. Material and methods: Records of CIA treated from 1997 to 2003 were reviewed. The prenatal ultrasound findings were correlated with SBS. Student's t and χ2 tests were performed to analyze epidemiological data, growth at discharge, sepsis, liver disease, catheter-related complications, motor developmental delay, and hospital stay in CIA with and without SBS. Results: Forty-four CIA: SBS developed in 43%, ranging from 83% in volvulus to 0% in complicated meconium ileus. Thirty-six prenatal diagnoses: a strong correlation with SBS was observed in isolated dilated bowel (58%). In SBS neonates, birth weight, gestational age, and growth at discharge were statistically lower, whereas sepsis, motor delay, and hospital stay were statistically higher. Conclusions: Many neonates with CIA detectable by prenatal ultrasound develop SBS. Short bowel syndrome presents a significant higher morbidity. The counseling should stress the frequent association between CIA and SBS as well as the significant morbidity in SBS.

Original languageEnglish
Pages (from-to)804-807
Number of pages4
JournalJournal of Pediatric Surgery
Volume41
Issue number4
DOIs
Publication statusPublished - Apr 2006

Keywords

  • Bowel obstruction
  • Counseling
  • Neonate
  • Prenatal diagnosis
  • Short bowel syndrome

ASJC Scopus subject areas

  • Surgery

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