Congenital intracranial mesenchymal chondrosarcoma: Case report and review of the literature in pediatric patients

Rossella De Cecio, Ilenia Migliaccio, Jessica Falleti, Marialaura Del Basso De Caro, Guido Pettinato

Research output: Contribution to journalArticle

Abstract

In this paper we report the 1st case of a congenital intracranial mesenchymal chondrosarcoma in a 2-month-old infant, apparently present at birth. A magnetic resonance image showed a large left parietal solid mass, while microscopy revealed a mixture of undifferentiated small cells and mature hyaline cartilage islands, positive for vimentin, S-100, and CD99. A surgical excision was performed but the patient died after a few weeks as a result of a rapid relapse of the tumor. We also review the pediatric cases (in patients less than 20 years old) of extraskeletal (intracranial) mesenchymal chondrosarcomas of the literature, with a focus on the most recent cytogenetic and immunohistochemical studies.

Original languageEnglish
Pages (from-to)309-313
Number of pages5
JournalPediatric and Developmental Pathology
Volume11
Issue number4
DOIs
Publication statusPublished - Jul 2008

Keywords

  • Congenital
  • Infant
  • Intracranial
  • Mesenchymal chondrosarcoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

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