Congenital leukemia: Persistent spontaneous regression in a patient with an acquired abnormal karyotype

Raffaele Sansone, Riccardo Haupt, Paolo Strigini, Maria Luisa Garrè, Claudio Panarello, Paolo Comaglia-Ferraris

Research output: Contribution to journalArticle

Abstract

Congential leukemia is a rare disease accounting for about 1% of all leukemias in childhood. While cases associated with Down’s syndrome not infrequently show a spontaneous regression, such an event is very rare in non-Down cases and exceptional in those (among the latter) which present clonal cytogenetic alterations in the neoplastic cells. We present the case of a patient with congenital leukemia and an abnormal karyotype (limited to the neoplastic clone), in which an apparently spontaneous and prolonged remission occurred after a relapse.

Original languageEnglish
Pages (from-to)48-50
Number of pages3
JournalActa Haematologica
Volume81
Issue number1
DOIs
Publication statusPublished - 1989

Keywords

  • Cytogenetics
  • Leukemia
  • Newborn
  • Spontaneous remission

ASJC Scopus subject areas

  • Hematology

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