Congenital leukemia: Persistent spontaneous regression in a patient with an acquired abnormal karyotype

Raffaele Sansone, Riccardo Haupt, Paolo Strigini, Maria Luisa Garrè, Claudio Panarello, Paolo Comaglia-Ferraris

Research output: Contribution to journalArticle

Abstract

Congential leukemia is a rare disease accounting for about 1% of all leukemias in childhood. While cases associated with Down’s syndrome not infrequently show a spontaneous regression, such an event is very rare in non-Down cases and exceptional in those (among the latter) which present clonal cytogenetic alterations in the neoplastic cells. We present the case of a patient with congenital leukemia and an abnormal karyotype (limited to the neoplastic clone), in which an apparently spontaneous and prolonged remission occurred after a relapse.

Original languageEnglish
Pages (from-to)48-50
Number of pages3
JournalActa Haematologica
Volume81
Issue number1
DOIs
Publication statusPublished - 1989

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Abnormal Karyotype
Leukemia
Spontaneous Remission
Rare Diseases
Down Syndrome
Cytogenetics
Clone Cells
Recurrence

Keywords

  • Cytogenetics
  • Leukemia
  • Newborn
  • Spontaneous remission

ASJC Scopus subject areas

  • Hematology

Cite this

Congenital leukemia : Persistent spontaneous regression in a patient with an acquired abnormal karyotype. / Sansone, Raffaele; Haupt, Riccardo; Strigini, Paolo; Garrè, Maria Luisa; Panarello, Claudio; Comaglia-Ferraris, Paolo.

In: Acta Haematologica, Vol. 81, No. 1, 1989, p. 48-50.

Research output: Contribution to journalArticle

Sansone, Raffaele ; Haupt, Riccardo ; Strigini, Paolo ; Garrè, Maria Luisa ; Panarello, Claudio ; Comaglia-Ferraris, Paolo. / Congenital leukemia : Persistent spontaneous regression in a patient with an acquired abnormal karyotype. In: Acta Haematologica. 1989 ; Vol. 81, No. 1. pp. 48-50.
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