We describe a 12-year-old girl with congenital myopathy. ATPase histochemical reactions and immunocytochemical analysis of muscle fiber-type composition with monoclonal antibodies against slow, fast (2 A and 2 B) and fetal myosin demonstrate that this congenital disease is characterized by type 2 A muscle fiber uniformity and smallness. This is an unusual feature for a congenital myopathy in which the fiber type predominance, when present, is confined to type I.
|Number of pages||4|
|Publication status||Published - 1992|
- Congenital myopathies
- Type 2 A fibers
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health