Abstract
We describe a 12-year-old girl with congenital myopathy. ATPase histochemical reactions and immunocytochemical analysis of muscle fiber-type composition with monoclonal antibodies against slow, fast (2 A and 2 B) and fetal myosin demonstrate that this congenital disease is characterized by type 2 A muscle fiber uniformity and smallness. This is an unusual feature for a congenital myopathy in which the fiber type predominance, when present, is confined to type I.
| Original language | English |
|---|---|
| Pages (from-to) | 10-13 |
| Number of pages | 4 |
| Journal | Neuropediatrics |
| Volume | 23 |
| Issue number | 1 |
| Publication status | Published - 1992 |
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Keywords
- Congenital myopathies
- Myosin
- Type 2 A fibers
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health
Cite this
Congenital myopathy with type 2 A muscle fiber uniformity and smallness. / Gallanti, A.; Prelle, A.; Chianese, L.; Barbieri, S.; Jann, S.; Schiaffino, S.; Comini, A.; Scarpini, E.; Pellegrini, G.; Moggio, M.; Scarlato, G.
In: Neuropediatrics, Vol. 23, No. 1, 1992, p. 10-13.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Congenital myopathy with type 2 A muscle fiber uniformity and smallness
AU - Gallanti, A.
AU - Prelle, A.
AU - Chianese, L.
AU - Barbieri, S.
AU - Jann, S.
AU - Schiaffino, S.
AU - Comini, A.
AU - Scarpini, E.
AU - Pellegrini, G.
AU - Moggio, M.
AU - Scarlato, G.
PY - 1992
Y1 - 1992
N2 - We describe a 12-year-old girl with congenital myopathy. ATPase histochemical reactions and immunocytochemical analysis of muscle fiber-type composition with monoclonal antibodies against slow, fast (2 A and 2 B) and fetal myosin demonstrate that this congenital disease is characterized by type 2 A muscle fiber uniformity and smallness. This is an unusual feature for a congenital myopathy in which the fiber type predominance, when present, is confined to type I.
AB - We describe a 12-year-old girl with congenital myopathy. ATPase histochemical reactions and immunocytochemical analysis of muscle fiber-type composition with monoclonal antibodies against slow, fast (2 A and 2 B) and fetal myosin demonstrate that this congenital disease is characterized by type 2 A muscle fiber uniformity and smallness. This is an unusual feature for a congenital myopathy in which the fiber type predominance, when present, is confined to type I.
KW - Congenital myopathies
KW - Myosin
KW - Type 2 A fibers
UR - http://www.scopus.com/inward/record.url?scp=20244387560&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20244387560&partnerID=8YFLogxK
M3 - Article
VL - 23
SP - 10
EP - 13
JO - Neuropediatrics
JF - Neuropediatrics
SN - 0174-304X
IS - 1
ER -