Congenital myopathy with type 2 A muscle fiber uniformity and smallness

A. Gallanti, A. Prelle, L. Chianese, S. Barbieri, S. Jann, S. Schiaffino, A. Comini, E. Scarpini, G. Pellegrini, M. Moggio, G. Scarlato

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We describe a 12-year-old girl with congenital myopathy. ATPase histochemical reactions and immunocytochemical analysis of muscle fiber-type composition with monoclonal antibodies against slow, fast (2 A and 2 B) and fetal myosin demonstrate that this congenital disease is characterized by type 2 A muscle fiber uniformity and smallness. This is an unusual feature for a congenital myopathy in which the fiber type predominance, when present, is confined to type I.

Original languageEnglish
Pages (from-to)10-13
Number of pages4
JournalNeuropediatrics
Volume23
Issue number1
Publication statusPublished - 1992

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Fast-Twitch Muscle Fibers
Myotonia Congenita
Nonmuscle Myosin Type IIB
Adenosine Triphosphatases
Monoclonal Antibodies
Muscles

Keywords

  • Congenital myopathies
  • Myosin
  • Type 2 A fibers

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

Cite this

Gallanti, A., Prelle, A., Chianese, L., Barbieri, S., Jann, S., Schiaffino, S., ... Scarlato, G. (1992). Congenital myopathy with type 2 A muscle fiber uniformity and smallness. Neuropediatrics, 23(1), 10-13.

Congenital myopathy with type 2 A muscle fiber uniformity and smallness. / Gallanti, A.; Prelle, A.; Chianese, L.; Barbieri, S.; Jann, S.; Schiaffino, S.; Comini, A.; Scarpini, E.; Pellegrini, G.; Moggio, M.; Scarlato, G.

In: Neuropediatrics, Vol. 23, No. 1, 1992, p. 10-13.

Research output: Contribution to journalArticle

Gallanti, A, Prelle, A, Chianese, L, Barbieri, S, Jann, S, Schiaffino, S, Comini, A, Scarpini, E, Pellegrini, G, Moggio, M & Scarlato, G 1992, 'Congenital myopathy with type 2 A muscle fiber uniformity and smallness', Neuropediatrics, vol. 23, no. 1, pp. 10-13.
Gallanti A, Prelle A, Chianese L, Barbieri S, Jann S, Schiaffino S et al. Congenital myopathy with type 2 A muscle fiber uniformity and smallness. Neuropediatrics. 1992;23(1):10-13.
Gallanti, A. ; Prelle, A. ; Chianese, L. ; Barbieri, S. ; Jann, S. ; Schiaffino, S. ; Comini, A. ; Scarpini, E. ; Pellegrini, G. ; Moggio, M. ; Scarlato, G. / Congenital myopathy with type 2 A muscle fiber uniformity and smallness. In: Neuropediatrics. 1992 ; Vol. 23, No. 1. pp. 10-13.
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