Abstract
We describe a 12-year-old girl with congenital myopathy. ATPase histochemical reactions and immunocytochemical analysis of muscle fiber-type composition with monoclonal antibodies against slow, fast (2 A and 2 B) and fetal myosin demonstrate that this congenital disease is characterized by type 2 A muscle fiber uniformity and smallness. This is an unusual feature for a congenital myopathy in which the fiber type predominance, when present, is confined to type I.
Original language | English |
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Pages (from-to) | 10-13 |
Number of pages | 4 |
Journal | Neuropediatrics |
Volume | 23 |
Issue number | 1 |
Publication status | Published - 1992 |
Keywords
- Congenital myopathies
- Myosin
- Type 2 A fibers
ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health