Connection of European particle therapy centers and generation of a common particle database system within the European ULICE-framework

Kerstin A. Kessel, Nina Bougatf, Christian Bohn, Daniel Habermehl, Dieter Oetzel, Rolf Bendl, Uwe Engelmann, Roberto Orecchia, Piero Fossati, Richard Pötter, Manjit Dosanjh, Jürgen Debus, Stephanie E. Combs

Research output: Contribution to journalArticlepeer-review


Background: To establish a common database on particle therapy for the evaluation of clinical studies integrating a large variety of voluminous datasets, different documentation styles, and various information systems, especially in the field of radiation oncology.Methods: We developed a web-based documentation system for transnational and multicenter clinical studies in particle therapy. 560 patients have been treated from November 2009 to September 2011. Protons, carbon ions or a combination of both, as well as a combination with photons were applied. To date, 12 studies have been initiated and more are in preparation.Results: It is possible to immediately access all patient information and exchange, store, process, and visualize text data, any DICOM images and multimedia data. Accessing the system and submitting clinical data is possible for internal and external users. Integrated into the hospital environment, data is imported both manually and automatically. Security and privacy protection as well as data validation and verification are ensured. Studies can be designed to fit individual needs.Conclusions: The described database provides a basis for documentation of large patient groups with specific and specialized questions to be answered. Having recently begun electronic documentation, it has become apparent that the benefits lie in the user-friendly and timely workflow for documentation. The ultimate goal is a simplification of research work, better study analyses quality and eventually, the improvement of treatment concepts by evaluating the effectiveness of particle therapy.

Original languageEnglish
Article number115
JournalRadiation Oncology
Issue number1
Publication statusPublished - Jul 24 2012


  • Documentation system
  • Multicenter clinical studies
  • Particle therapy

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging


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