Documento di consenso sulla biopsia endomiocardica promosso dall'Associazione per la Patologia Cardiovascolare Italiana.

Translated title of the contribution: Consensus document on endomyocardial biopsy of the Associazione per la Patologia Cardiovascolare Italiana

Ornella Leone, Claudio Rapezzi, Gianfranco Sinagra, Annalisa Angelini, Eloisa Arbustini, Giovanni Bartoloni, Cristina Basso, Alida L P Caforio, Fiorella Calabrese, Fabio Coccolo, Giulia d'Amati, Emiliano Mariesi, Ornella Milanesi, Savina Nodari, Fabrizio Oliva, Andrea Perkan, Daniela Prandstraller, Angela Pucci, Angelo Ramondo, Furio SilvestriMarialuisa Valente, Gaetano Thiene

Research output: Contribution to journalArticlepeer-review

Abstract

The Italian Scientific Associations of Cardiologists and Cardiovascular Pathologists have produced this consensus document on the diagnostic role of endomyocardial biopsy (EMB) in terms of techniques, analysis and reporting. The document is intended for clinical cardiologists, hemodynamic experts, electrophysiologists, surgical pathologists, and cardiac surgeons. It has three main aims: a) to collocate EMB in the context of currently available tools for diagnosis of heart diseases; b) to provide recommendations for rational implementation; c) to outline key characteristics (standards) for Italian cardiology and surgical pathology centers that perform and analyze EMB. A general lack of prospective, controlled studies addressing EMB prohibited the use of traditional evidence-based recommendations that rely on classes of available evidence. Thus, it was agreed that three key points should be taken into account: a) the specific pathology to be diagnosed (or excluded); b) the existence of any alternative, non-invasive diagnostic techniques; c) the overall consequences of reaching a definite diagnosis on patients' clinical management. Accordingly, we propose recommendations for EMB based on the following levels of diagnostic value: level 1: no alternative method exists to reach a definite diagnosis that can have obvious consequences for clinical management; level 2a: no alternative method exists to reach a definite diagnosis; however, the implications for clinical management are uncertain; level 2b: no alternative method exists to reach a definite diagnosis; however, the diagnosis would not influence clinical management; level 3: an alternative method exists to reach a definite diagnosis. The second part of the document proposes current protocols for the preparation, analysis and reporting of EMB in the context of each main pathologic entity. Particular attention is given to tissue characterization and implementation of molecular tests.

Translated title of the contributionConsensus document on endomyocardial biopsy of the Associazione per la Patologia Cardiovascolare Italiana
Original languageItalian
JournalGiornale Italiano di Cardiologia
Volume10
Issue number9 Suppl 1
Publication statusPublished - Sep 2009

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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