Consensus statement on the diagnosis of multiple system atrophy

Sid Gilman, Phillip Low, Niall Quinn, Alberto Albanese, Yoav Ben-Shlomo, Clare Fowler, Horacio Kaufmann, Thomas Klockgether, Anthony Lang, Peter Lantos, Irene Litvan, Christopher Mathias, Eugene Oliver, David Robertson, Irwin Schatz, Gregor Wenning

Research output: Contribution to journalArticle

Abstract

We report the results of a consensus conference on the diagnosis of multiple system atrophy (MSA). We describe the clinical features of the disease, which include four domains: autonomic failure/urinary dysfunction, parkinsonism and cerebellar ataxia, and corticospinal dysfunction. We set criteria to define the relative importance of these features. The diagnosis of possible MSA requires one criterion plus two features from separate domains. The diagnosis of probable MSA requires the criterion for autonomic failure/urinary dysfunction plus poor levodopa responsive parkinsonism or cerebellar ataxia. The diagnosis of definite MSA requires pathological confirmation.

Original languageEnglish
Pages (from-to)359-362
Number of pages4
JournalClinical Autonomic Research
Volume8
Issue number6
DOIs
Publication statusPublished - 1998

Keywords

  • Autonomic insufficiency
  • Cerebellar ataxia
  • Glial cytoplasmic inclusions
  • Multiple system atrophy
  • Parkinsonism
  • Urinary dysfunction

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Consensus statement on the diagnosis of multiple system atrophy'. Together they form a unique fingerprint.

  • Cite this

    Gilman, S., Low, P., Quinn, N., Albanese, A., Ben-Shlomo, Y., Fowler, C., Kaufmann, H., Klockgether, T., Lang, A., Lantos, P., Litvan, I., Mathias, C., Oliver, E., Robertson, D., Schatz, I., & Wenning, G. (1998). Consensus statement on the diagnosis of multiple system atrophy. Clinical Autonomic Research, 8(6), 359-362. https://doi.org/10.1007/BF02309628