Consensus statements on ablative radiotherapy for oligometastatic prostate cancer: A position paper of Italian Association of Radiotherapy and Clinical Oncology (AIRO)

Rolando M. D'Angelillo, Giulio Francolini, Gianluca Ingrosso, Vincenzo Ravo, Luca Triggiani, Alessandro Magli, Ercole Mazzeo, Stefano Arcangeli, Filippo Alongi, Barbara A. Jereczek-Fossa, Stefano Pergolizzi, Giovanni L. Pappagallo, Stefano M. Magrini

Research output: Contribution to journalReview articlepeer-review

Abstract

Oligometastatic prostate cancer comprises a wide spectrum of conditions, ranging from de novo oligometastatic cancer at diagnosis to oligometastatic castration-resistant disease, which are distinct entities in terms of biology and prognosis. In order to clarify and standardize the clinical role of ablative radiotherapy in oligometastatic prostate cancer, the Italian Association of Radiotherapy and Clinical Oncology (AIRO) formed an expert panel to review the current literature and develop a formal consensus. Oligometastatic prostate cancer was defined as the presence of up to three metastatic lesions involving bones or nodes outside pelvis. Thereafter, four clinical scenarios were explored: metastatic castration-sensitive disease at diagnosis and after primary treatment, and metastatic castration-resistant disease at diagnosis and during treatment, where the role of ablative radiotherapy was defined either in conjunction with systemic therapy or as the only treatment in selected cases. This paper summarizes the current literature about these issues and the proposed recommendations.

Original languageEnglish
Pages (from-to)24-28
Number of pages5
JournalCritical Reviews in Oncology/Hematology
Volume138
DOIs
Publication statusPublished - Jun 1 2019

Keywords

  • Ablative radiotherapy
  • Oligometastatic
  • Prostate cancer
  • SABR
  • SBRT
  • Stereotactic radiotherapy

ASJC Scopus subject areas

  • Hematology
  • Oncology

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