Conservative surgery in breast cancer. Significance of resection margins

M. Gennaro, C. Ferraris, V. Guida, G. Tomasic, M. L. Carcangiu, M. Greco

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

We approached the issue of surgical margins in the conservative treatment of breast cancer by examining the literature germane to four precise questions: At what distance from the macroscopic margin of the tumour should the resection margin be? To what extent do histologically clear resection margins indicate complete local control of the disease? To what extent do histologically involved margins indicate persistence of disease? and Does the local recurrence rate correlate with the status of the resection margin? We propose categorizing margin involvement into five groups (absent, focal, minimal, moderate and extensive involvement) according to strict histological criteria, and assigning increasingly aggressive subsequent treatments according to the extent of any margin involvement.

Original languageEnglish
Pages (from-to)432-437
Number of pages6
JournalBreast
Volume10
Issue number5
DOIs
Publication statusPublished - 2001

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Breast Neoplasms
Recurrence
Margins of Excision
Neoplasms
Therapeutics
Conservative Treatment

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Conservative surgery in breast cancer. Significance of resection margins. / Gennaro, M.; Ferraris, C.; Guida, V.; Tomasic, G.; Carcangiu, M. L.; Greco, M.

In: Breast, Vol. 10, No. 5, 2001, p. 432-437.

Research output: Contribution to journalArticle

Gennaro, M. ; Ferraris, C. ; Guida, V. ; Tomasic, G. ; Carcangiu, M. L. ; Greco, M. / Conservative surgery in breast cancer. Significance of resection margins. In: Breast. 2001 ; Vol. 10, No. 5. pp. 432-437.
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