Conservative surgery in high-risk epithelial ovarian carcinoma

Francesco Raspagliesi, Rosanna Fontanelli, Dario Paladini, Emanuela M. Di Re

Research output: Contribution to journalArticle

Abstract

Background: In epithelial ovarian cancer, conservative surgery has mainly been adopted for stage Ia disease. The aim of this study is to report on a conservative surgical approach used in selected young patients with ovarian cancer who would usually undergo radical operations. Study Design: From 1980 through 1994, 10 patients with invasive epithelial ovarian cancer and with high-grade or limited extraovarian disease were treated with conservative surgery. The mean age was 22.7 years. The stage was Ia grade 3 in 2 patients, Ic in 2 patients, IIIa in 2 patients, and IIIc in 4 patients. Eight patients were given adjuvant therapy (radiotherapy in 1 and chemotherapy in 7). Results: All patients were alive and disease-free at a median followup time of 70 months (range 24-138 months). Nine patients were menstruating regularly and three had become pregnant. Conclusions: It seems that in selected patients, conservative operations can be used beyond the worldwide accepted criterion of stage Ia. This concept deserves additional investigation in larger series.

Original languageEnglish
Pages (from-to)457-460
Number of pages4
JournalJournal of the American College of Surgeons
Volume185
Issue number5
DOIs
Publication statusPublished - 1997

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Carcinoma
Adjuvant Radiotherapy
Ovarian Neoplasms
Drug Therapy

ASJC Scopus subject areas

  • Surgery

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Conservative surgery in high-risk epithelial ovarian carcinoma. / Raspagliesi, Francesco; Fontanelli, Rosanna; Paladini, Dario; Di Re, Emanuela M.

In: Journal of the American College of Surgeons, Vol. 185, No. 5, 1997, p. 457-460.

Research output: Contribution to journalArticle

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